Melioidosis: an Australian perspective

S Smith, J Hanson, BJ Currie - Tropical medicine and infectious disease, 2018 - mdpi.com
Burkholderia pseudomallei is endemic in northern Australia, with cases of melioidosis most
commonly occurring during the wet season in individuals with diabetes, hazardous alcohol …

Melioidosis in Africa: time to uncover the true disease load

I Steinmetz, GE Wagner, E Kanyala… - Tropical medicine and …, 2018 - mdpi.com
Melioidosis is an often fatal infectious disease with a protean clinical spectrum, caused by
the environmental bacterial pathogen Burkholderia pseudomallei. Although the disease has …

Development and validation of a Burkholderia pseudomallei core genome multilocus sequence typing scheme to facilitate molecular surveillance

S Lichtenegger, TT Trinh, K Assig, K Prior… - Journal of Clinical …, 2021 - Am Soc Microbiol
Burkholderia pseudomallei causes the severe disease melioidosis. Whole-genome
sequencing (WGS)-based typing methods currently offer the highest resolution for molecular …

Whole-genome sequencing of Burkholderia pseudomallei from an urban melioidosis hot spot reveals a fine-scale population structure and localised spatial clustering …

A Rachlin, M Mayo, JR Webb, M Kleinecke, V Rigas… - Scientific reports, 2020 - nature.com
Melioidosis is a severe disease caused by the environmental bacterium Burkholderia
pseudomallei that affects both humans and animals throughout northern Australia …

Myanmar Burkholderia pseudomallei strains are genetically diverse and originate from Asia with phylogenetic evidence of reintroductions from neighbouring …

JR Webb, MM Win, KN Zin, KKN Win, TT Wah… - Scientific reports, 2020 - nature.com
Melioidosis was first identified in Myanmar in 1911 but for the last century it has remained
largely unreported there. Burkholderia pseudomallei was first isolated from the environment …

Comparative genomics confirms a rare melioidosis human-to-human transmission event and reveals incorrect phylogenomic reconstruction due to polyclonality

A Aziz, BJ Currie, M Mayo, DS Sarovich… - Microbial …, 2020 - microbiologyresearch.org
Human-to-human transmission of the melioidosis bacterium, Burkholderia pseudomallei, is
exceedingly rare, with only a handful of suspected cases documented to date. Here, we …

Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity

C Lood, C Peeters, Q Lamy-Besnier… - PLoS …, 2021 - journals.plos.org
Burkholderia multivorans is a member of the Burkholderia cepacia complex (Bcc), notorious
for its pathogenicity in persons with cystic fibrosis. Epidemiological surveillance suggests …

Analysis of fine-scale phylogeny of Burkholderia pseudomallei in relation to regional geography and drug susceptibility in Thailand

Y Hinwan, P Chareonsudjai, P Reungsang… - Scientific Reports, 2024 - nature.com
Melioidosis caused by Burkholderia pseudomallei (Bp) is a public health threat. Genomic-
epidemiology research on this deadly disease is scarce. We investigated whole-genome …

Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a

SP Wongpalee, H Thananchai… - PLoS Neglected …, 2022 - journals.plos.org
Detection of Burkholderia pseudomallei, a causative bacterium for melioidosis, remains a
challenging undertaking due to long assay time, laboratory requirements, and the lack of …

Phylogeographic, genomic, and meropenem susceptibility analysis of Burkholderia ubonensis

EP Price, DS Sarovich, JR Webb, CM Hall… - PLoS neglected …, 2017 - journals.plos.org
The bacterium Burkholderia ubonensis is commonly co-isolated from environmental
specimens harbouring the melioidosis pathogen, Burkholderia pseudomallei. B. ubonensis …