Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation

GF Nieman, LA Gatto, P Andrews, J Satalin… - Annals of intensive …, 2020 - Springer
Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at
approximately 39%. One of the only treatments is supportive: mechanical ventilation …

Functional lung imaging with synchrotron radiation: Methods and preclinical applications

S Bayat, L Porra, P Suortti, W Thomlinson - Physica Medica, 2020 - Elsevier
Many lung disease processes are characterized by structural and functional heterogeneity
that is not directly appreciable with traditional physiological measurements. Experimental …

Hysteresis and lung recruitment in acute respiratory distress syndrome patients: a CT scan study

D Chiumello, JM Arnal, M Umbrello… - Critical care …, 2020 - journals.lww.com
Objectives: Hysteresis of the respiratory system pressure-volume curve is related to alveolar
surface forces, lung stress relaxation, and tidal reexpansion/collapse. Hysteresis has been …

Gravitational distribution of regional opening and closing pressures, hysteresis and atelectrauma in ARDS evaluated by electrical impedance tomography

G Scaramuzzo, E Spinelli, S Spadaro, A Santini… - Critical Care, 2020 - Springer
Background The physiological behavior of lungs affected by the acute respiratory distress
syndrome (ARDS) differs between inspiration and expiration and presents heterogeneous …

Quantification de l'aération pulmonaire sur des images CT de patients atteints du syndrome de détresse respiratoire aiguë

L Penarrubia - 2022 - theses.hal.science
Le syndrome de détresse respiratoire aiguë (SDRA) provoque un dérèglement de l'équilibre
vital entre oxygène apporté et dioxyde de carbone évacué par le système respiratoire. En …

Regional pleural strain measurements during mechanical ventilation using ultrasound elastography: A randomized, crossover, proof of concept physiologic study

M Girard, MH Roy Cardinal, M Chassé… - Frontiers in …, 2022 - frontiersin.org
Background Mechanical ventilation is a common therapy in operating rooms and intensive
care units. When ill-adapted, it can lead to ventilator-induced lung injury (VILI), which is …

Acute Respiratory Distress Syndrome (ARDS): Pathophysiological Insights and Lung Imaging

G Perchiazzi, H Wrigge - Journal of Clinical Medicine, 2019 - mdpi.com
Acute respiratory distress syndrome (ARDS) is in the center of the scientific debate both for
its complex pathophysiology and for the discussion about the remedies that could contribute …

[PDF][PDF] Martin Girard1, 2, 3*, Marie-Hélène Roy Cardinal4, Michaël Chassé2, 5, Sébastien Garneau1, Yiorgos Alexandros Cavayas6, Guy Cloutier4, 7 and André Y …

M Girard, MH Roy Cardinal, M Chassé, S Garneau… - 2022 - academia.edu
While often a live-saving therapy and a necessity during general anesthesia, mechanical
ventilation may promote lung damage when ill-adapted, a phenomenon called …

A novel closed-circuit mechanical ventilation system to assess lung mechanics during xenon synchrotron radiation imaging

S POLETTO - 2019 - politesi.polimi.it
Subjects with impaired lung function often require mechanical ventilation. The identification
of the optimal mechanical conditions of the lung able to maximize gas exchange without …