Antioxidant therapies in traumatic brain injury
Due to a multiplicity of causes provoking traumatic brain injury (TBI), TBI is a highly
heterogeneous pathology, characterized by high mortality and disability rates. TBI is an …
heterogeneous pathology, characterized by high mortality and disability rates. TBI is an …
Flavonoids as a natural enhancer of neuroplasticity—An overview of the mechanism of neurorestorative action
N Cichon, J Saluk-Bijak, L Gorniak, L Przyslo, M Bijak - Antioxidants, 2020 - mdpi.com
Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …
However, it is of particular importance in the case of central nervous system (CNS) …
[HTML][HTML] Regulatory mechanism of icariin in cardiovascular and neurological diseases
Y Wang, C Shang, Y Zhang, L Xin, L Jiao… - Biomedicine & …, 2023 - Elsevier
Cardiovascular diseases (CVDs) and neurological diseases are widespread diseases with
substantial rates of morbidity and mortality around the world. For the past few years, the …
substantial rates of morbidity and mortality around the world. For the past few years, the …
(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice
D Lecca, M Bader, D Tweedie, AF Hoffman… - Neurobiology of …, 2019 - Elsevier
Mild traumatic brain injury (mTBI) is a risk factor for neurodegenerative disorders, such as
Alzheimer's disease (AD) and Parkinson's disease (PD). TBI-derived neuropathologies are …
Alzheimer's disease (AD) and Parkinson's disease (PD). TBI-derived neuropathologies are …
Icariin promotes survival, proliferation, and differentiation of neural stem cells in vitro and in a rat model of Alzheimer's disease
D Ma, L Zhao, L Zhang, Y Li, L Zhang… - Stem cells …, 2021 - Wiley Online Library
Alzheimer's disease (AD) involves the degeneration of cholinergic neurons in the basal
forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic …
forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic …
[HTML][HTML] Folicitin abrogates scopolamine induced oxidative stress, hyperlipidemia mediated neuronal synapse and memory dysfunction in mice
No effective drug treatment is available for Alzheimer disease, thus the need arise to
develop efficient drugs for its treatment. Natural products have pronounced capability in …
develop efficient drugs for its treatment. Natural products have pronounced capability in …
[HTML][HTML] Novel synthetic and natural therapies for traumatic brain injury
D Battaglini, D Siwicka-Gieroba… - Current …, 2021 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is a major cause of disability and death worldwide. The initial
mechanical insult results in tissue and vascular disruption with hemorrhages and cellular …
mechanical insult results in tissue and vascular disruption with hemorrhages and cellular …
The pros and cons of motor, memory, and emotion-related behavioral tests in the mouse traumatic brain injury model
R Zhang, J Wang, L Huang, TJ Wang… - Neurological …, 2022 - Taylor & Francis
Traumatic brain injury (TBI) is a medical emergency with high morbidity and mortality. Motor,
memory, and emotion-related deficits are common symptoms following TBI, yet treatment is …
memory, and emotion-related deficits are common symptoms following TBI, yet treatment is …
Cardioprotective effect of icariin against myocardial fibrosis and its molecular mechanism in diabetic cardiomyopathy based on network pharmacology: Role of ICA in …
L Zhang, S Wang, Y Li, Y Wang, C Dong, H Xu - Phytomedicine, 2021 - Elsevier
Background Diabetic cardiomyopathy (DCM) is one of the most severe symptoms of
diabetes. It continues to be a major clinical problem, but our knowledge of its molecular …
diabetes. It continues to be a major clinical problem, but our knowledge of its molecular …
Intradermal Injection of Icariin-HP-β-cyclodextrin improved traumatic brain injury via the trigeminal epineurium-brain dura pathway
W Yang, YH Han, HC Wang, CT Lu, XC Yu… - Journal of Drug …, 2022 - Taylor & Francis
The lower bioavailability after oral administration limited icariin applications in central
nervous system. Icariin/HP-β-cyclodextrin (HP-β-CD) inclusion complex was prepared for …
nervous system. Icariin/HP-β-cyclodextrin (HP-β-CD) inclusion complex was prepared for …