Inhibition of growth of the malaria parasite Plasmodium falciparum by known translation-
inhibitory antibiotics has generated interest in understanding their action on the translation …

The conversion of 1‐deoxy‐d‐xylulose‐5‐phosphate (DOXP) to 2‐C‐methyl‐d‐erythritol‐4‐
phosphate (MEP) is effectively blocked by 1‐deoxy‐d‐xylulose‐5‐phosphate …

After the discovery of antibacterial chemicals and antibiotics through the 1950s by empirical
assays based on growth inhibition, methods gradually evolved to encompass more directed …

Lincomycin and clindamycin are the only members of the relatively small lincosamide
antimicrobial class marketed for use in humans. This paper only reviews data regarding …

Abstract Blocking the 2‐C‐methyl‐d‐erythrithol‐4‐phosphate pathway for isoprenoid
biosynthesis offers new ways to inhibit the growth of Plasmodium spp. Fosmidomycin [(3‐(N …

Although there are potent antimalarial drugs available, the spread of drug resistance has led
to an increase in morbidity and mortality rates in malaria-endemic regions. To overcome …

Coagulase-positive staphylococci, which frequently colonize the mucosal surfaces of
animals, also cause a spectrum of opportunistic infections including skin and soft tissue …

Sažetak Malaria is a serious worldwide medical issue that results in substantial annual
death and morbidity. The availability of treatment alternatives is limited, and the rise of …

In Plasmodium falciparum, the formation of isopentenyl diphosphate and dimethylallyl
diphosphate, central intermediates in the biosynthesis of isoprenoids, occurs via the …

An important goal of nanotechnology is the application of individual molecule handling
techniques to the discovery of potential new therapeutic agents. Of particular interest is the …