Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …

Intracellular membrane traffic defines a complex network of pathways that connects many of
the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by …

Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …

Lipid incorporation from endoplasmic reticulum (ER) to lipid droplet (LD) is important in
controlling LD growth and intracellular lipid homeostasis. However, the molecular link …

The secretory pathway is responsible for the synthesis, folding, and delivery of a diverse
array of cellular proteins. Secretory protein synthesis begins in the endoplasmic reticulum …

Neurotransmitter release is governed by proteins that have homo-logs in most types of
intracellular membrane fusion, including the Sec1/Munc18 protein Munc18-1 and the …

The fusion of transport vesicles with their target membranes is fundamental for intracellular
membrane trafficking and diverse physiological processes and is driven by the assembly of …

Protein secretion is an essential process for living organisms. In eukaryotes, this
encompasses numerous steps mediated by several hundred cellular proteins. The core …

Intracellular trafficking entails the budding, transport, tethering, and fusion of transport
vesicles and other membrane carriers. Here we review recent progress toward a …

COPI‐coated vesicles mediate transport between Golgi stacks and retrograde transport from
the Golgi to the endoplasmic reticulum. The COPI coat exists as a stable heptameric …