Natural products as modulators of Nrf2 signaling pathway in neuroprotection
I Moratilla-Rivera, M Sánchez… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …
[HTML][HTML] Nrf2: An all-rounder in depression
C Zuo, H Cao, Y Song, Z Gu, Y Huang, Y Yang, J Miao… - Redox biology, 2022 - Elsevier
The balance between oxidation and antioxidant is crucial for maintaining homeostasis. Once
disrupted, it can lead to various pathological outcomes and diseases, such as depression …
disrupted, it can lead to various pathological outcomes and diseases, such as depression …
[HTML][HTML] Targeting neuroinflammation by polyphenols: A promising therapeutic approach against inflammation-associated depression
Depression is the most prevalent and debilitating mental disorder that affects a substantial
number of people globally, hindering all aspects of their lives and leading to a high number …
number of people globally, hindering all aspects of their lives and leading to a high number …
Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update
S Chen, Y Tang, Y Gao, K Nie, H Wang, H Su… - Frontiers in …, 2022 - frontiersin.org
Depression is a global health problem with growing prevalence rates and serious impacts
on the daily life of patients. However, the side effects of currently used antidepressants …
on the daily life of patients. However, the side effects of currently used antidepressants …
Anti-Inflammatory, Antioxidant, and Neuroprotective Effects of Polyphenols—Polyphenols as an Element of Diet Therapy in Depressive Disorders
A Winiarska-Mieczan, M Kwiecień… - International Journal of …, 2023 - mdpi.com
Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …
countries, the percentage of patients with depressive disorders may be as high as 10 …
Flavonols in action: Targeting oxidative stress and neuroinflammation in major depressive disorder
Major depressive disorder is one of the most common mental illnesses that highly impairs
quality of life. Pharmacological interventions are mainly focused on altered monoamine …
quality of life. Pharmacological interventions are mainly focused on altered monoamine …
Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action
P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …
the rise, but drug therapies are rarely curative. Functional disorders and the organic …
Quercetin alleviates the progression of breast cancer‐related depression via inhibiting the Pyroptosis and promoting the immune response
Q Zhu, L Yang, H Yang, Y Han… - Mediators of …, 2022 - Wiley Online Library
Background. Breast cancer‐related depression (BCRD) seriously inhibits the life quality of
patients with breast cancer. The Xiaoyao Kangai Jieyu Formula is known to inhibit the …
patients with breast cancer. The Xiaoyao Kangai Jieyu Formula is known to inhibit the …
The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline
J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …
The Nrf2 pathway in depressive disorders: a systematic review of animal and human studies
G Sani, S Margoni, A Brugnami, OM Ferrara… - Antioxidants, 2023 - mdpi.com
There is increasing interest in the involvement of antioxidative systems in protecting from
depression. Among these, Nrf2 occupies a central place. We aimed to review the role of Nrf2 …
depression. Among these, Nrf2 occupies a central place. We aimed to review the role of Nrf2 …