Macrophages in immunoregulation and therapeutics
S Chen, AFUH Saeed, Q Liu, Q Jiang, H Xu… - … and Targeted Therapy, 2023 - nature.com
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …
and are a vital part of the innate immune system for host defense against many pathogens …
The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer
JL Galeano Niño, H Wu, KD LaCourse… - Nature, 2022 - nature.com
The tumour-associated microbiota is an intrinsic component of the tumour microenvironment
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
Z Yuan, Y Li, S Zhang, X Wang, H Dou, X Yu, Z Zhang… - Molecular cancer, 2023 - Springer
The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
Cancer cell plasticity during tumor progression, metastasis and response to therapy
A Pérez-González, K Bévant, C Blanpain - Nature cancer, 2023 - nature.com
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
Dynamic EMT: a multi‐tool for tumor progression
S Brabletz, H Schuhwerk, T Brabletz… - The EMBO journal, 2021 - embopress.org
The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
Distinct contributions of partial and full EMT to breast cancer malignancy
F Lüönd, N Sugiyama, R Bill, L Bornes, C Hager… - Developmental cell, 2021 - cell.com
Epithelial-mesenchymal transition (EMT) is a transient, reversible process of cell de-
differentiation where cancer cells transit between various stages of an EMT continuum …
differentiation where cancer cells transit between various stages of an EMT continuum …
Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Linking EMT programmes to normal and neoplastic epithelial stem cells
AW Lambert, RA Weinberg - Nature Reviews Cancer, 2021 - nature.com
Epithelial stem cells serve critical physiological functions in the generation, maintenance
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
EMT, MET, plasticity, and tumor metastasis
B Bakir, AM Chiarella, JR Pitarresi, AK Rustgi - Trends in cell biology, 2020 - cell.com
Cancer cell identity and plasticity are required in transition states, such as epithelial–
mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET), in primary …
mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET), in primary …