Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …
G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …
[HTML][HTML] Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …
preclinical models and emerging evidence in humans have established the crucial roles of …
[PDF][PDF] Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
S Xu, O Chaudhary, P Rodríguez-Morales, X Sun… - Immunity, 2021 - cell.com
A common metabolic alteration in the tumor microenvironment (TME) is lipid accumulation, a
feature associated with immune dysfunction. Here, we examined how CD8+ tumor infiltrating …
feature associated with immune dysfunction. Here, we examined how CD8+ tumor infiltrating …
[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
[PDF][PDF] Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity
Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …
membranes, and regulate energy metabolism. Questions remain as to which lipid species …
Mechanistic insights into the oxidized low‐density lipoprotein‐induced atherosclerosis
C Khatana, NK Saini, S Chakrabarti… - Oxidative medicine …, 2020 - Wiley Online Library
Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …
Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
U Förstermann, N Xia, H Li - Circulation research, 2017 - Am Heart Assoc
Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice
Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues,
including atherosclerotic lesions, and frequently mediate proinflammatory changes …
including atherosclerotic lesions, and frequently mediate proinflammatory changes …
An update on lipid oxidation and inflammation in cardiovascular diseases
S Zhong, L Li, X Shen, Q Li, W Xu, X Wang… - Free Radical Biology …, 2019 - Elsevier
Cardiovascular diseases (CVD), including ischemic heart diseases and cerebrovascular
diseases, are the leading causes of morbidity and mortality worldwide. Atherosclerosis is the …
diseases, are the leading causes of morbidity and mortality worldwide. Atherosclerosis is the …