Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus–infected mice

CH GeurtsvanKessel, MAM Willart, IM Bergen… - Journal of Experimental …, 2009 - rupress.org
Tertiary lymphoid organs (TLOs) are organized aggregates of B and T cells formed in
postembryonic life in response to chronic immune responses to infectious agents or self …

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

A Didierlaurent, J Goulding, S Patel… - The Journal of …, 2008 - rupress.org
The World Health Organization estimates that lower respiratory tract infections (excluding
tuberculosis) account for∼ 35% of all deaths caused by infectious diseases. In many cases …

Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity

S Falck‐Jones, B Österberg… - Journal of Internal …, 2023 - Wiley Online Library
Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …

The expanding role (s) of eosinophils in health and disease

EA Jacobsen, RA Helmers, JJ Lee… - Blood, The Journal of …, 2012 - ashpublications.org
Surprisingly, the role (s) of eosinophils in health and disease is often summarized by
clinicians and basic research scientists as a pervasive consensus opinion first learned in …

The role of dendritic and epithelial cells as master regulators of allergic airway inflammation

BN Lambrecht, H Hammad - The Lancet, 2010 - thelancet.com
Lung dendritic cells bridge innate and adaptive immunity, integrating a variety of stimuli from
allergens, microbial colonisation, environmental pollution, and innate immune cells into a …

5-HT and the immune system

GP Ahern - Current opinion in pharmacology, 2011 - Elsevier
The classical neurotransmitter, serotonin (5-HT), plays an important role outside of the
central nervous system in immune signaling. Here I review recent studies describing 5-HT …

[HTML][HTML] Estrogen signaling modulates allergic inflammation and contributes to sex differences in asthma

A Keselman, N Heller - Frontiers in immunology, 2015 - frontiersin.org
Asthma is a chronic airway inflammatory disease that affects~ 300 million people worldwide.
It is characterized by airway constriction that leads to wheezing, coughing, and shortness of …

The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

H Tang, W Cao, SP Kasturi, R Ravindran… - Nature …, 2010 - nature.com
The mechanisms that initiate T helper type 2 (TH2) responses are poorly understood. Here
we demonstrate that cysteine protease–induced TH2 responses occur via'cooperation' …

Airway remodeling contributes to the progressive loss of lung function in asthma: an overview

RM Pascual, SP Peters - Journal of Allergy and Clinical Immunology, 2005 - Elsevier
Airway inflammation, airflow obstruction, and bronchial hyperresponsiveness are
characteristic phenotypic features of asthma. Clinically, airflow obstruction in asthma often is …

Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation

CD Sadik, AD Luster - Journal of leukocyte biology, 2012 - academic.oup.com
Chemoattractants are pivotal mediators of host defense, orchestrating the recruitment of
immune cells into sites of infection and inflammation. Chemoattractants display vast …