Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

Sex differences in endurance running

T Besson, R Macchi, J Rossi, CYM Morio, Y Kunimasa… - Sports medicine, 2022 - Springer
In recent years, there has been a significant expansion in female participation in endurance
(road and trail) running. The often reported sex differences in maximal oxygen uptake (V …

Understanding the female athlete: molecular mechanisms underpinning menstrual phase differences in exercise metabolism

T Oosthuyse, JA Strauss, AC Hackney - European Journal of Applied …, 2023 - Springer
Research should equitably reflect responses in men and women. Including women in
research, however, necessitates an understanding of the ovarian hormones and menstrual …

The effect of the menstrual cycle on exercise metabolism: implications for exercise performance in eumenorrhoeic women

T Oosthuyse, AN Bosch - Sports medicine, 2010 - Springer
The female hormones, oestrogen and progesterone, fluctuate predictably across the
menstrual cycle in naturally cycling eumenorrhoeic women. Other than reproductive …

[HTML][HTML] Gender differences in skeletal muscle substrate metabolism–molecular mechanisms and insulin sensitivity

AM Lundsgaard, B Kiens - Frontiers in endocrinology, 2014 - frontiersin.org
It has become increasingly apparent that substrate metabolism is subject to gender-specific
regulation, and the aim of this review is to outline the available evidence of molecular …

Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise

AM Lundsgaard, AM Fritzen, B Kiens - Trends in Endocrinology & …, 2018 - cell.com
This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …

[HTML][HTML] Glucose uptake by skeletal muscle within the contexts of type 2 diabetes and exercise: an integrated approach

NA Hulett, RL Scalzo, JEB Reusch - Nutrients, 2022 - mdpi.com
Type 2 diabetes continues to negatively impact the health of millions. The inability to
respond to insulin to clear blood glucose (insulin resistance) is a key pathogenic driver of …

Menstrual cycle hormones and oral contraceptives: a multimethod systems physiology-based review of their impact on key aspects of female physiology

AC D'Souza, M Wageh, JS Williams… - Journal of Applied …, 2023 - journals.physiology.org
Hormonal changes around ovulation divide the menstrual cycle (MC) into the follicular and
luteal phases. In addition, oral contraceptives (OCs) have active (higher hormone) and …

AMPK and the biochemistry of exercise: implications for human health and disease

EA Richter, NB Ruderman - Biochemical Journal, 2009 - portlandpress.com
AMPK (AMP-activated protein kinase) is a phylogenetically conserved fuel-sensing enzyme
that is present in all mammalian cells. During exercise, it is activated in skeletal muscle in …

Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study

MC Venables, J Achten… - Journal of applied …, 2005 - journals.physiology.org
The aim of the present study was to establish fat oxidation rates over a range of exercise
intensities in a large group of healthy men and women. It was hypothesised that exercise …