[HTML][HTML] Plant-made vaccines against viral diseases in humans and farm animals

H Su, A Van Eerde, E Rimstad, R Bock… - Frontiers in plant …, 2023 - frontiersin.org
Plants provide not only food and feed, but also herbal medicines and various raw materials
for industry. Moreover, plants can be green factories producing high value bioproducts such …

[HTML][HTML] Recent advances in protective vaccines against hepatitis viruses: A narrative review

A Elbahrawy, H Atalla, M Alboraie, A Alwassief… - Viruses, 2023 - mdpi.com
Vaccination has been confirmed to be the safest and, sometimes, the only tool of defense
against threats from infectious diseases. The successful history of vaccination is evident in …

Immunogenicity and safety of a 3-antigen hepatitis B vaccine vs a single-antigen hepatitis B vaccine: a phase 3 randomized clinical trial

T Vesikari, A Finn, P Van Damme… - JAMA network …, 2021 - jamanetwork.com
Importance There is a need for improved immunogenicity of hepatitis B virus (HBV) vaccines
among young adults with risk of infection. Objectives To demonstrate manufacturing …

[HTML][HTML] HBV vaccines: advances and development

F Mahmood, R Xu, MUN Awan, Y Song, Q Han, X Xia… - Vaccines, 2023 - mdpi.com
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …

[HTML][HTML] Insights into induction of the immune response by the hepatitis B vaccine

FA Di Lello, AP Martínez… - World Journal of …, 2022 - ncbi.nlm.nih.gov
After more than four decades of hepatitis B virus (HBV) vaccine implementation, its safety
and efficacy in preventing HBV infection have been proven and several milestones have …

[HTML][HTML] A therapeutic hepatitis B mRNA vaccine with strong immunogenicity and persistent virological suppression

H Zhao, X Shao, Y Yu, L Huang, NP Amor, K Guo… - npj Vaccines, 2024 - nature.com
Here we report on the development and comprehensive evaluations of an mRNA vaccine for
chronic hepatitis B (CHB) treatment. In two different HBV carrier mouse models generated by …

The “humanized” N‐glycosylation pathway in CRISPR/Cas9‐edited Nicotiana benthamiana significantly enhances the immunogenicity of a S/preS1 Hepatitis B Virus …

AM Pantazica, A van Eerde, MO Dobrica… - Plant biotechnology …, 2023 - Wiley Online Library
The recent SARS‐CoV‐2 pandemic has taught the world a costly lesson about the
devastating consequences of viral disease outbreaks but also, the remarkable impact of …

[HTML][HTML] Hepatitis B vaccination: A historical overview with a focus on the Italian achievements

L Romano', AR Zanetti - Viruses, 2022 - mdpi.com
Vaccination is the most effective way to control and prevent acute and chronic hepatitis B,
including cirrhosis and HCC, on a global scale. According to WHO recommendations, 190 …

Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection …

L Piermatteo, S D'Anna, A Bertoli… - Emerging Microbes & …, 2023 - Taylor & Francis
Specific HBsAg mutations are known to hamper HBsAg recognition by neutralizing
antibodies thus challenging HBV-vaccination efficacy. Nevertheless, information on their …

PreHevbrio: the first approved 3-antigen hepatitis B vaccine

T Vesikari, JM Langley, V Popovic… - Expert Review of …, 2023 - Taylor & Francis
Introduction Hepatitis B remains a major cause of death and morbidity worldwide. Universal
childhood immunization programs have been very successful, but many adults remain …