The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …

The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) continue to
endanger public health. Here, we report the synthesis of neolignan isomagnolone (I) and its …

Unique coumarin aminophosphonates as new antibacterial agents were designed and
synthesized to combat severely bacterial resistance. Bioactivity assessment identified that 3 …

Unique coumarin conjugates with thiazolidinone as novel structural antibacterial modulators
were exploited to combat the lethal multidrug-resistant bacterial infections. Bioactivity …

Natural berberine-derived azolyl ethanols as new structural antibacterial agents were
designed and synthesized for fighting with dreadful bacterial resistance. Partial target …

Novel carbazole-oxadiazoles were developed as new potential antibacterial agents to
combat dreadful resistance. Some target compounds displayed predominant inhibitory …

The increasing incidence of antibiotic resistance has forced the development of unique
antimicrobials with novel multitargeting mechanisms to combat infectious diseases caused …

New efficient antimicrobial agents are urgently needed to combat invasive multidrug-
resistant pathogens infections. Structurally unique benzenesulfonyl thiazoloimines (BSTIs) …

A unique class of antibacterial azolylpyrimidinediols (APDs) and their analogues were
developed. Some synthesized compounds showed excellent bacteriostatic potency; …