CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice

Y Lu, S Oura, T Matsumura, A Oji… - Biology of …, 2019 - academic.oup.com
More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet
many of them remain unstudied in terms of their roles in spermatogenesis and sperm …

The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: scrotal ultrasound reference ranges and associations with clinical, seminal, and …

F Lotti, F Frizza, G Balercia, A Barbonetti, HM Behre… - …, 2021 - Wiley Online Library
Abstract Background Scrotal color Doppler ultrasound (CDUS) still suffers from lack of
standardization. Hence, the European Academy of Andrology (EAA) has promoted a …

Management of premature ejaculation: a clinical guideline from the Italian Society of Andrology and Sexual Medicine (SIAMS)

A Sansone, A Aversa, G Corona, AD Fisher… - Journal of …, 2021 - Springer
Premature ejaculation (PE) is the most prevalent male sexual dysfunction, and the most
recently defined. PE is often mistakenly considered a purely psychosexological symptom by …

[HTML][HTML] Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations

M Bertolotto, S Freeman, J Richenberg, J Belfield… - Journal of …, 2020 - Springer
Although often asymptomatic and detected incidentally, varicocele is a relatively common
problem in patients who seek medical attention for infertility problems. Ultrasound (US) is the …

[HTML][HTML] Metabolic syndrome and reproduction

F Lotti, S Marchiani, G Corona, M Maggi - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) and infertility are two afflictions with a high prevalence in the
general population. MetS is a global health problem increasing worldwide, while infertility …

Effects of diabetes mellitus on sperm quality and fertility outcomes: Clinical evidence

F Lotti, M Maggi - Andrology, 2023 - Wiley Online Library
Background Diabetes mellitus is a global epidemic characterized by high morbidity and
mortality. Diabetes mellitus can lead to acute and chronic systemic complications. Among …

[HTML][HTML] Melatonin relieves heat-induced spermatocyte apoptosis in mouse testes by inhibition of ATF6 and PERK signaling pathways

DZ Qin, H Cai, C He, DH Yang, J Sun, WL He… - Zoological …, 2021 - ncbi.nlm.nih.gov
Normal spermatogenic processes require the scrotal temperature to be lower than that of the
body as excessive heat affects spermatogenesis in the testes, reduces sperm quality and …

Loss of SPACA1 function causes autosomal recessive globozoospermia by damaging the acrosome–acroplaxome complex

P Chen, H Saiyin, R Shi, B Liu, X Han… - Human …, 2021 - academic.oup.com
STUDY QUESTION Is the sperm acrosome membrane-associated protein 1 (SPACA1) gene
critical to human globozoospermia? SUMMARY ANSWER The biallelic loss-of-function …

The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: An overview on male genital tract ultrasound reference ranges

F Lotti, F Frizza, G Balercia, A Barbonetti, HM Behre… - …, 2022 - Wiley Online Library
Background So far, male genital tract color‐Doppler ultrasound (MGT‐CDUS) was not
standardized. Recently, the European Academy of Andrology (EAA) published the results of …

AI tools for assessing human fertility using risk factors: A state-of-the-art review

D GhoshRoy, PA Alvi, KC Santosh - Journal of Medical Systems, 2023 - Springer
Infertility has massively disrupted social and marital life, resulting in stressful emotional well-
being. Early diagnosis is the utmost need for faster adaption to respond to these changes …