Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …

Objective Peroxisome injury occurs in the central nervous system (CNS) during multiple
virus infections that result in neurological disabilities. We investigated host neuroimmune …

Two isoforms of the peroxisomal targeting signal type 1 (PTS1) receptor, termed Pex5pS
and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 …

To investigate peroxisome assembly and human peroxisome biogenesis disorders (PBDs)
such as Zellweger syndrome, thirteen different complementation groups (CGs) of Chinese …

Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …

Peroxisomes are a class of structurally and functionally related organelles present in almost
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …

Targeting of peroxisomal membrane proteins (PMPs) is a multistep process that requires not
only recognition of PMPs in the cytosol but also their insertion into the peroxisomal …

Two distinct pathways have recently been proposed for the import of peroxisomal membrane
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …

Peroxisomes are degraded by a selective type of autophagy known as pexophagy. Several
different types of pexophagy have been reported in mammalian cells. However, the …