Abstract Purpose of Review We review the current evidence for medical and surgical
treatments of spontaneous intracerebral hemorrhage (ICH). Recent Findings Therapy with …

A new generation of antithrombotic agents has recently emerged. These provide direct
inhibition of either thrombin (factor IIa [FIIa]) or FXa, and are increasingly replacing the …

Abstract Background Direct oral anticoagulants (DOACs) have shown a positive benefit-risk
balance in both clinical trials and real-world data, but approximately 2% to 3.5% of patients …

Importance Intracerebral hemorrhage (ICH) is the most devastating adverse event in
patients receiving oral anticoagulation. There is only sparse evidence regarding ICH related …

In recent years, several direct‐acting oral anticoagulants (DOAC) have become available for
use in Europe and other regions in indications related to prophylaxis and treatment of …

Acute gastrointestinal bleeding represents the most common adverse event associated with
the use of oral anticoagulant therapy. Due to increasing prescription of anticoagulants …

Background Although the need for an emergency intervention may merit laboratory
measurement of non-vitamin K antagonist oral anticoagulant (NOAC) concentration or …

Background Direct (non-vitamin-K-dependent) oral anticoagulants (DOAC) are given as an
alternative to vitamin K antagonists (VKA) to prevent stroke and embolic disease in patients …

Gastrointestinal bleeding (GIB) is a potentially fatal and avoidable medical condition that
poses a burden on global health care costs. The rate of major GIB related to the use of some …

In clinical practice, the number of patients treated with direct oral anticoagulants (DOACs)
has consistently increased over the years. Since anticoagulant therapy has been associated …