Traditional Chinese Medicine: A promising strategy to regulate the imbalance of bacterial flora, impaired intestinal barrier and immune function attributed to ulcerative …

M Wang, R Fu, D Xu, Y Chen, S Yue, S Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Globally, plant materials are widely used as an additional
and alternative therapy for the treating of diverse diseases. Ulcerative colitis (UC) is a …

Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions

RA Oliveira, EG Pamer - Cell Host & Microbe, 2023 - cell.com
Increasing experimental evidence suggests that administering live commensal bacterial
species can optimize microbiome composition and lead to reduced disease severity and …

Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice

J Sun, J Xu, Y Ling, F Wang, T Gong, C Yang… - Translational …, 2019 - nature.com
Alzheimer's disease (AD) is the most common dementia in the elderly. Treatment for AD is
still a difficult task in clinic. AD is associated with abnormal gut microbiota. However, little is …

Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota

M Wu, P Li, Y An, J Ren, D Yan, J Cui, D Li, M Li… - Pharmacological …, 2019 - Elsevier
Phloretin, extracted from the pericarp and velamen of apples or pears, is a dihydrochalcone
flavonoid with anti-bacterial and anti-inflammatory activities. It has been reported that …

The aryl hydrocarbon receptor (AHR) as a potential target for the control of intestinal inflammation: insights from an immune and bacteria sensor receptor

L Pernomian, M Duarte-Silva… - Clinical reviews in …, 2020 - Springer
The aryl hydrocarbon receptor (AHR) is widely expressed in immune and non-immune cells
of the gut and its activation has been correlated to the outcome of inflammatory bowel …

Gut dysbiosis contributes to the imbalance of Treg and Th17 cells in Graves' disease patients by propionic acid

X Su, X Yin, Y Liu, X Yan, S Zhang… - The Journal of …, 2020 - academic.oup.com
Background Graves' disease (GD) is a typical organ-specific autoimmune disease. Intestinal
flora plays a pivotal role in immune homeostasis and autoimmune disease development …

Procedures for fecal microbiota transplantation in murine microbiome studies

SC Bokoliya, Y Dorsett, H Panier… - Frontiers in cellular and …, 2021 - frontiersin.org
Fecal microbiota transplantation (FMT) has been widely recognized as an approach to
determine the microbiome's causal role in gut dysbiosis-related disease models and as a …

Fecal microbiota transplantation for the treatment of inflammatory bowel disease: an update

P Tan, X Li, J Shen, Q Feng - Frontiers in pharmacology, 2020 - frontiersin.org
Fecal microbiota transplantation (FMT) has successfully been applied for the treatment of
recurrent Clostridioides difficile infection (CDI), which has led to studies on its application to …

[HTML][HTML] Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation

CJG Pinto, MÁ Ávila-Gálvez, Y Lian, P Moura-Alves… - Redox Biology, 2023 - Elsevier
Abstract The Aryl Hydrocarbon Receptor (AHR) is a ligand-dependent transcription factor
able to control complex transcriptional processes in several cell types, which has been …

Probiotic-based intervention in the treatment of ulcerative colitis: conventional and new approaches

J Štofilová, M Kvaková, A Kamlárová, E Hijová… - Biomedicines, 2022 - mdpi.com
Although there are number of available therapies for ulcerative colitis (UC), many patients
are unresponsive to these treatments or experience secondary failure during treatment …