Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Embryonic heart development is an intricate process that mainly involves morphogens,
transcription factors, and cardiac genes. The precise spatiotemporal expression of these …

Background Pulmonary arterial hypertension (PAH) is a rare disease characterized by
distinctive changes in pulmonary arterioles that lead to progressive pulmonary arterial …

Congenital heart disease (CHD) is the most common birth defect worldwide and the number
one killer of live-born infants in the United States. Heart development occurs early in …

The mortality rate of cardiovascular diseases (CVD) in China is on the rise. The increasing
burden of CVD in China has become a major public health problem. Cyanobacterial blooms …

About a quarter of the human diseases occurs for exposure to air pollution. The male
reproductive system, and especially spermatogenesis, seems to be particularly sensitive. As …

The clinical variability seen in BAV aortopathy, in terms of phenotype and natural/clinical
history, suggests complex interactions between primary genetic defects, other modifier …

Objectives: We investigated the association of working hours with occupational injuries in
hospital shift work. Methods: Registry data of occupational injuries of hospital employees …

Congenital heart disease (CHD), the most common form of developmental abnormality in
humans, remains a leading cause of morbidity and mortality in neonates. Genetic defects …

Newborns with congenital heart defects tend to have a higher risk of growth restriction,
which can be an independent risk factor for adverse outcomes. To date, a systematic review …