I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Key Clinical Points Chronic Rhinosinusitis with Nasal Polyps Chronic rhinosinusitis with
nasal polyps typically manifests as nasal obstruction, reduction in sense of smell, nasal …

Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

Chronic rhinosinusitis (CRS) is a complex heterogeneous disease with different phenotypes
and endotypes. Recent advances in our understanding of the pathogenetic mechanisms of …

Background Chronic rhinosinusitis (CRS) is a complex disease that incorporates many
different conditions. Currently, primary CRS is considered a disease of broad airway …

Biologic therapy is a new treatment option for patients with chronic rhinosinusitis with nasal
polyps (CRSwNP). Currently, the only biologic with Food and Drug Administration–approval …

Advances in understanding the pathogenic mechanisms of both rhinitis and chronic
rhinosinusitis have resulted in new treatment options, especially for chronic rhinosinusitis. A …

Keywords: chronic rhinosinusitis; corticosteroid implant; endoscopic sinus surgery; nasal
polyps; T2 biologic; topical corticosteroid; treatment algorithm EN chronic rhinosinusitis …