[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution
H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …
modification-editing processes and to some extent repair mechanisms. Each chapter offers …
PTEN promoter methylation in sporadic thyroid carcinomas
F Alvarez-Nuñez, E Bussaglia, D Mauricio, J Ybarra… - Thyroid, 2006 - liebertpub.com
The tumor-suppressor gene PTEN/MMAC1, on chromosome 10q23. 3, has been implicated
in an important number of human tumors, such as thyroid carcinomas. PTEN somatic …
in an important number of human tumors, such as thyroid carcinomas. PTEN somatic …
Epigenomics and epigenetic therapy of cancer
R Brown, G Strathdee - Trends in molecular medicine, 2002 - cell.com
Epigenetic inactivation of genes that are crucial for the control of normal cell growth is a
hallmark of cancer cells. These epigenetic mechanisms include crosstalk between DNA …
hallmark of cancer cells. These epigenetic mechanisms include crosstalk between DNA …
Early adversity and developmental outcomes: Interaction between genetics, epigenetics, and social experiences across the life span
FA Champagne - Perspectives on psychological science, 2010 - journals.sagepub.com
Longitudinal studies in humans demonstrate the association between prenatal and
postnatal experiences of adversity and long-term changes in neurodevelopment. These …
postnatal experiences of adversity and long-term changes in neurodevelopment. These …
O 6 -methyl-guanine-DNA methyltransferase Methylation in Serum and Tumor DNA Predicts …
C Balana, JL Ramirez, M Taron, Y Roussos, A Ariza… - Clinical cancer …, 2003 - AACR
Purpose: In glioblastoma multiforme (GBM), the cytotoxic effect of 1, 3-bis (2-chloroethyl)-1-
nitrosourea (BCNU) and temozolamide is dependent on O 6 alkylation, which correlates …
nitrosourea (BCNU) and temozolamide is dependent on O 6 alkylation, which correlates …
MHC class I antigens and immune surveillance in transformed cells
MHC class I antigens play a crucial role in the interaction of tumor cells with the host immune
system, in particular, in the presentation of peptides as tumor‐associated antigens to …
system, in particular, in the presentation of peptides as tumor‐associated antigens to …
[HTML][HTML] p16 promoter hypermethylation: a useful serum marker for early detection of gastric cancer
AIM: To determine p16 promoter hypermethylation in gastric tumoral tissue and serum
samples, its impact on p16-protein expression, and correlation with clinical and histological …
samples, its impact on p16-protein expression, and correlation with clinical and histological …
Inactivation of HOXA Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis
G Strathdee, TL Holyoake, A Sim, A Parker… - Clinical Cancer …, 2007 - AACR
Purpose: The HOX genes comprise a large family of homeodomain-containing transcription
factors, present in four separate clusters, which are key regulators of embryonic …
factors, present in four separate clusters, which are key regulators of embryonic …
Appraising the causal relevance of DNA methylation for risk of lung cancer
Background DNA methylation changes in peripheral blood have recently been identified in
relation to lung cancer risk. Some of these changes have been suggested to mediate part of …
relation to lung cancer risk. Some of these changes have been suggested to mediate part of …
Nanopore-based assay for detection of methylation in double-stranded DNA fragments
J Shim, Y Kim, GI Humphreys, AM Nardulli, F Kosari… - ACS …, 2015 - ACS Publications
DNA methylation is an epigenetic modification of DNA in which methyl groups are added at
the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated …
the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated …