Nanopore fabrication via the controlled dielectric breakdown (CDB) method offers an
opportunity to create solid-state nanopores directly in salt solution with sub-nanometer …

Die Forschungsergebnisse des Human-Genom-Projektes sind Ausgangspunkt für das
Verständnis zahlreicher biologischer Phänomene. Dies ist das erste Buch, das die Rolle des …

AIM: To investigated whether sall3 transcription was regulated by promoter CpG island
hypermethylation in hepatocellular carcinoma (HCC). METHODS: The cell lines Huh7 …

Background CCAAT/enhancer binding protein-delta (C/EBP-delta) is a member of the highly
conserved C/EBP family of basic region leucine zipper transcription factors. C/EBP family …

Methods: A total of 88 epithelial ovarian cancer (EOC) tissue samples, 14 low malignant
potential (LMP) tumours and 20 benign ovarian tissue samples were analysed for MGMT …

Abstract Aim Abnormal hypermethylation of CpG islands associated with tumor suppressor
genes can lead to transcriptional silencing in neoplasia. The aim of this study was to …

We developed a simple and highly-selective method for 5-methylcytosine detection of
specific gene sequence based on binary-probe DNA hybridization. The sequence …

Environmental exposures can have profound consequences for health and development,
and epigenetic modifications have been proposed as a mechanism for these effects. In …

We report on two sibs with ICF syndrome (immunodeficiency, centromeric heterochromatin
instability, and facial anomalies) diagnosed in the elder brother based on the typical …