[HTML][HTML] DNA methylation analysis of the tumor suppressor gene CDKN2B in Brazilian leukemia patients

PSP Lima, GA Molffeta, AG Araujo, MA Zago… - … and Molecular Biology, 2008 - SciELO Brasil
The aim of this work was to evaluate the methylation profile of the p15 (CDKN2B) gene in
Brazilian patients with leukemia and to correlate the CDKN2B gene expression with the …

Патогенетические эффекты нестабильности эмбрионального генома в развитии человека

ИН Лебедев, ТВ Никитина, АГ Токарева… - Информационный …, 2006 - elibrary.ru
Для онтогенеза человека характерна чрезвычайно высокая частота репродуктивных
потерь, в значительной степени обусловленная геномными мутациями. Несмотря на …

Methylation status of RB1 promoter in Indian retinoblastoma patients

B Joseph, G Mamatha, G Raman… - Cancer biology & …, 2004 - Taylor & Francis
Retinoblastoma can arise due to mutational inactivation or methylation of RB1 gene
promoter. A 600-bp CpG island consisting of the essential promoter is present at the 5'end of …

DNA 甲基化在钚辐射损伤机制中的研究进展

刘晓明, 古晓娜, 苏丽霞, 张艳娜 - 辐射防护, 2023 - journal01.magtech.org.cn
常规辐射流行病学在评价低剂量辐射生物效应方面存在一定的局限性, 利用分子生物学方法研究
辐射人群远后健康效应是目前辐射流行病学研究的主要趋势. 本文对DNA 甲基化, 生物学意义 …

Plasma Cell-Free Adenomatous Polyposis Coli Gene Promoter Methylation as a Prognostic Biomarker for Hepatocellular Carcinoma

CY Hsiao, CY Lu, HJ Su, KW Huang - Oncology, 2024 - karger.com
Introduction: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide.
Lack of biomarkers for follow-up after treatment is a clinical challenge. DNA methylation has …

[PDF][PDF] Tetrahydrofurane is a component of annona muricata leaf will induce apoptosis program in cancer cell because the virus: A proxy for cancer treatment

A Prayitno, AN Artanti, VS Dewangga… - Immunome …, 2016 - academia.edu
Introduction: The compound that allegedly derived from acetogenin has a mechanism of
inhibition complex of mitochondrial. Inhibition complex of mitochondrial by acetogenin will …

[PDF][PDF] Genetics for the practicing dermatologist

JD Feramisco, H Tsao, DH Siegel - Seminars in cutaneous …, 2010 - cdn.mdedge.com
In the era of robust genome sequencing, a working understanding of genetics has become
important for the clinician. For the dermatologist, understanding the flow of genetic …

Association between response to primary treatments and MGMT status in glioblastoma

E Franceschi, A Tosoni, E Pozzati… - Expert Review of …, 2008 - Taylor & Francis
The median overall survival and, more importantly, the 2-year survival rate of patients with
newly diagnosed glioblastoma are increased by the administration of combined …

[PDF][PDF] Del código genético al código epigenético: Nuevas estrategias terapéuticas

JI Neissa, C Guerrero - Revista de la Facultad de Medicina, 2004 - revistas.unal.edu.co
El papel crítico del remodelamiento de la cromatina en la expresión de los genes se halla
bajo la influencia de los cambios epigenéticos que conforman un lenguaje inesperado en el …

PUMA 基因在肝癌组织的表达及意义

朱丹荣, 陈吉祥, 陈明军 - 江苏医药, 2012 - cqvip.com
目的研究p53 正向细胞凋亡调控因子(PUMA) 基因mRNA 及其功能蛋白在肝癌组织中的表达及
其临床意义. 方法用半定量RT-PCR 和Western blot 方法检测42 例肝癌患者的癌组织及其癌旁 …