[HTML][HTML] Emerging biomarkers for early detection of chronic kidney disease

M Mizdrak, M Kumrić, TT Kurir, J Božić - Journal of personalized …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a major and serious global health problem that leads to
kidney damage as well as multiple systemic diseases. Early diagnosis and treatment are two …

[HTML][HTML] New potential biomarkers for chronic kidney disease management—A review of the literature

I Lousa, F Reis, I Beirão, R Alves, L Belo… - International Journal of …, 2020 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

Regulatory network and targeted interventions for CCDC family in tumor pathogenesis

Z Liu, W Yan, S Liu, Z Liu, P Xu, W Fang - Cancer letters, 2023 - Elsevier
CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins.
There are about 180 CCDC family genes, encoding proteins that are involved in intercellular …

[HTML][HTML] Causal effects of systemic inflammatory regulators on chronic kidney diseases and renal function: a bidirectional Mendelian randomization study

H Li, M Li, C Liu, P He, A Dong, S Dong… - Frontiers in …, 2023 - frontiersin.org
Background While targeted systemic inflammatory modulators show promise in preventing
chronic kidney disease (CKD) progression, the causal link between specific inflammatory …

Coiled-coil domain-containing (CCDC) proteins: functional roles in general and male reproductive physiology

PP Priyanka, S Yenugu - Reproductive Sciences, 2021 - Springer
The coiled-coil domain-containing (CCDC) proteins have been implicated in a variety of
physiological and pathological processes. Their functional roles vary from their interaction …

[HTML][HTML] The signaling pathway of TNF receptors: Linking animal models of renal disease to human CKD

I Lousa, F Reis, A Santos-Silva, L Belo - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) has been recognized as a global public health problem.
Despite the current advances in medicine, CKD-associated morbidity and mortality remain …

[HTML][HTML] Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease

E Petra, J Siwy, A Vlahou, J Jankowski - PLoS One, 2022 - journals.plos.org
Chronic kidney disease (CKD) is characterized by the loss of kidney function. The molecular
mechanisms underlying the development and progression of CKD are still not fully …

Chitosan/genipin modified electrode for voltammetric determination of interleukin-6 as a biomarker of sepsis

F de Matos Morawski, GBM Dias, KAP Sousa… - International Journal of …, 2023 - Elsevier
Ultrasensitive electroanalytical monitoring of interleukin-6 levels in serum samples has
emerged as a valuable tool for the early diagnosis of inflammatory diseases. Despite its …

[HTML][HTML] New insights into molecular mechanisms of chronic kidney disease

W Frąk, J Kućmierz, M Szlagor, E Młynarska, J Rysz… - Biomedicines, 2022 - mdpi.com
Chronic kidney disease (CKD) is a major public health problem with a developing incidence
and prevalence. As a consequence of the growing number of patients diagnosed with renal …

[PDF][PDF] The oxidative status in patients with chronic kidney disease

V Vasylchenko, L Korol, O Kuchmenko, N Stepanova - 2020 - ekmair.ukma.edu.ua
An excess of free radicals accompanies the development of renal pathologies and causes
numerous concomitant complications and syndromes. The most common of these are …