A brief review of cardiovascular diseases, associated risk factors and current treatment regimes

GD Flora, MK Nayak - Current pharmaceutical design, 2019 - ingentaconnect.com
Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …

Gender differences in cardiovascular prophylaxis: Focus on antiplatelet treatment

P Di Giosia, G Passacquale, M Petrarca… - Pharmacological …, 2017 - Elsevier
Cardiovascular disease (CVD) represents the leading cause of death worldwide, and
equally affects both sexes although women develop disease at an older age than men. A …

Safety of glycoprotein IIb-IIIa inhibitors used in stroke-related treatment: a systematic review and meta-analysis

X Zhu, G Cao - Clinical and Applied Thrombosis/Hemostasis, 2020 - journals.sagepub.com
Background: Endovascular therapy and intravenous thrombolysis with recombinant tissue
plasminogen activator are the 2 most recommended treatments for acute ischemic stroke …

[HTML][HTML] STEMI care 2021: Addressing the knowledge gaps

M Yildiz, SR Wade, TD Henry - American Heart Journal Plus: Cardiology …, 2021 - Elsevier
Tremendous progress has been made in the treatment of ST-segment elevation myocardial
infarction (STEMI), the most severe and time-sensitive acute coronary syndrome. Primary …

Antiplatelet agents for chronic kidney disease

P Natale, SC Palmer, VM Saglimbene… - Cochrane Database …, 2022 - cochranelibrary.com
Background Antiplatelet agents are widely used to prevent cardiovascular events. The risks
and benefits of antiplatelet agents may be different in people with chronic kidney disease …

Integrins: integrating the biology and therapy of cell–cell interactions

F Pandolfi, L Franza, S Altamura, C Mandolini… - Clinical …, 2017 - Elsevier
Purpose Although the role of integrins has been described in a variety of diseases, these
roles seem to be distinct. To date, no study has attempted to provide links to the various …

Antithrombotic and antiplatelet drug toxicity

DB Liss, ME Mullins - Critical Care Clinics, 2021 - criticalcare.theclinics.com
Significant progress has been made in the development of medications to prevent
thrombosis and platelet aggregation. These drugs target specific components of the …

Dual antiplatelet and anticoagulant (APAC) heparin proteoglycan mimetic with shear-dependent effects on platelet-collagen binding and thrombin generation

J Chen, CC Verni, A Jouppila, R Lassila… - Thrombosis research, 2018 - Elsevier
Heparin proteoglycans (HEP-PGs) carry standard heparin-mediated anticoagulant
properties as well as novel antiplatelet functions, a combination that may be significant for …

Meta-analysis of randomized controlled trials on the efficacy and safety of intracoronary administration of tirofiban for no-reflow phenomenon

T Qin, L Xie, MH Chen - BMC cardiovascular disorders, 2013 - Springer
Background Currently, there is still a lack of an optimal treatment for no-reflow phenomenon
(NR). The aim of this simple meta-analysis was to evaluate the efficacy and safety of …

Neurocritical care of emergent large-vessel occlusion: the era of a new standard of care

F Al-Mufti, E Dancour, K Amuluru… - Journal of Intensive …, 2017 - journals.sagepub.com
Acute ischemic stroke continues to be one of the leading causes of morbidity and mortality
worldwide. Recent advances in mechanical thrombectomy techniques combined with …