Reactive oxygen species (ROS) are mainly produced in mitochondria and are involved in
various physiological activities of the ovary through signaling and are critical for regulating …

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early
depletion of the ovarian follicle pool accompanied by an earlier-than-normal loss of fertility in …

Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the
production of reactive oxygen species (ROS) and the body's ability to detoxify and neutralize …

Aging has a major detrimental effect on the optimal function of the ovary with changes in this
organ preceding the age-related deterioration in other tissues, with the middle-aged …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Several studies and research papers have been published to elucidate and understand the
mechanism of the coronavirus disease 2019 (COVID-19) pandemic and its long-term effects …

The decline in oocyte quality with age is an irreversible process that results in low fertility.
Reproductive aging causes an increase in oocyte aneuploidy leading to a decrease in …

Prolonging the reproductive lifespan is beneficial for preserving the physical and
psychological health of women. The transplantation of mesenchymal stem cell (MSC) …

Cholesterol is an important precursor necessary for the synthesis of steroid hormones and
other functional substances. This study conducted a 28-day feeding experiment to assess …

The ovarian microenvironment becomes fibrotic and stiff with age, in part due to increased
collagen and decreased hyaluronan. However, the extracellular matrix (ECM) is a complex …