The future of cardiovascular stents: bioresorbable and integrated biosensor technology

D Hoare, A Bussooa, S Neale, N Mirzai… - Advanced …, 2019 - Wiley Online Library
Cardiovascular disease is the greatest cause of death worldwide. Atherosclerosis is the
underlying pathology responsible for two thirds of these deaths. It is the age‐dependent …

Improving PCI outcomes using postprocedural physiology and intravascular imaging

LJC van Zandvoort, Z Ali, M Kern… - Cardiovascular …, 2021 - jacc.org
Although clinical outcomes after percutaneous coronary intervention (PCI) are improving,
the long-term risk for target vessel failure remains concerning. Although the application of …

Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a …

ZA Ali, A Maehara, P Généreux, RA Shlofmitz… - The Lancet, 2016 - thelancet.com
Background Percutaneous coronary intervention (PCI) is most commonly guided by
angiography alone. Intravascular ultrasound (IVUS) guidance has been shown to reduce …

Blinded physiological assessment of residual ischemia after successful angiographic percutaneous coronary intervention: the DEFINE PCI study

A Jeremias, JE Davies, A Maehara… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study sought to evaluate the incidence and causes of an abnormal
instantaneous wave-free ratio (iFR) after angiographically successful percutaneous …

1-Year outcomes of blinded physiological assessment of residual ischemia after successful PCI: DEFINE PCI trial

MR Patel, A Jeremias, A Maehara, M Matsumura… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to identify the post–percutaneous coronary intervention
(PCI) target value of instantaneous wave-free ratio (iFR) that would best discriminate clinical …

FFR-guided PCI optimization directed by high-definition IVUS versus standard of care: the FFR REACT trial

T Neleman, LJC van Zandvoort… - Cardiovascular …, 2022 - jacc.org
Background Post–percutaneous coronary intervention (PCI) fractional flow reserve (FFR)<
0.90 is common and has been related to impaired patient outcome. Objectives The authors …

[HTML][HTML] Angiography-based fractional flow reserve: state of the art

A Scoccia, M Tomaniak, T Neleman… - Current cardiology …, 2022 - Springer
Abstract Purpose of Review Three-dimensional quantitative coronary angiography-based
methods of fractional flow reserve (FFR) derivation have emerged as an appealing …

Explanation of postprocedural fractional flow reserve below 0.85: a comprehensive ultrasound analysis of the FFR SEARCH registry

LJC van Zandvoort, K Masdjedi, K Witberg… - Circulation …, 2019 - Am Heart Assoc
Background: Fractional flow reserve (FFR) after percutaneous coronary intervention is a
predictor of adverse cardiovascular events during follow-up. However, the rationale for low …

Routine fractional flow reserve measurement after percutaneous coronary intervention: the FFR-SEARCH study

RJ van Bommel, K Masdjedi, R Diletti… - Circulation …, 2019 - Am Heart Assoc
Background: Fractional flow reserve (FFR) is the current gold standard to determine
hemodynamic severity of angiographically intermediate coronary lesions. Much less is …

[HTML][HTML] What are the causes of a suboptimal FFR after coronary stent deployment? Insights from a consecutive series using OCT imaging

M Wolfrum, GL De Maria, S Benenati… - …, 2018 - eurointervention.pcronline.com
Aims: Fractional flow reserve (FFR) can be used to detect a suboptimal result after
percutaneous coronary intervention (PCI). A lower post-procedure FFR (< 0.90) has been …