Global spread and persistence of dengue
JL Kyle, E Harris - Annu. Rev. Microbiol., 2008 - annualreviews.org
Dengue is a spectrum of disease caused by four serotypes of the most prevalent arthropod-
borne virus affecting humans today, and its incidence has increased dramatically in the past …
borne virus affecting humans today, and its incidence has increased dramatically in the past …
Vaccine development as a means to control dengue virus pathogenesis: do we know enough?
TC Pierson, MS Diamond - Annual Review of Virology, 2014 - annualreviews.org
Dengue virus (DENV) is a mosquito-transmitted RNA virus responsible for 390 million
infections each year and significant morbidity and mortality throughout tropical and …
infections each year and significant morbidity and mortality throughout tropical and …
Zika virus infection enhances future risk of severe dengue disease
LC Katzelnick, C Narvaez, S Arguello… - Science, 2020 - science.org
The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …
Antibody-dependent enhancement of severe dengue disease in humans
LC Katzelnick, L Gresh, ME Halloran, JC Mercado… - Science, 2017 - science.org
For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to
enhance viral replication in vitro and severe disease in animal models. Although suspected …
enhance viral replication in vitro and severe disease in animal models. Although suspected …
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection
Preexisting cross-reactive antibodies have been implicated in both protection and
pathogenesis during subsequent infections with different dengue virus (DENV) serotypes …
pathogenesis during subsequent infections with different dengue virus (DENV) serotypes …
Antibody-based assay discriminates Zika virus infection from other flaviviruses
A Balmaseda, K Stettler… - Proceedings of the …, 2017 - National Acad Sciences
Zika virus (ZIKV) is a mosquito-borne flavivirus that emerged recently as a global health
threat, causing a pandemic in the Americas. ZIKV infection mostly causes mild disease, but …
threat, causing a pandemic in the Americas. ZIKV infection mostly causes mild disease, but …
Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity
M OhAinle, A Balmaseda, AR Macalalad… - Science translational …, 2011 - science.org
The rapid spread of dengue is a worldwide public health problem. In two clinical studies of
dengue in Managua, Nicaragua, we observed an abrupt increase in disease severity across …
dengue in Managua, Nicaragua, we observed an abrupt increase in disease severity across …
Symptomatic versus inapparent outcome in repeat dengue virus infections is influenced by the time interval between infections and study year
Four dengue virus serotypes (DENV1-4) circulate globally, causing more human illness than
any other arthropod-borne virus. Dengue can present as a range of clinical manifestations …
any other arthropod-borne virus. Dengue can present as a range of clinical manifestations …
Longitudinal analysis of antibody cross-neutralization following Zika virus and dengue virus infection in Asia and the Americas
Background The 4 dengue virus serotypes (DENV1–4) and Zika virus (ZIKV) are related
mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies and …
mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies and …
Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term
LC Katzelnick, JV Zambrana, D Elizondo… - Science translational …, 2021 - science.org
Dengue virus serotypes 1 to 4 (DENV1–4) and Zika virus (ZIKV) are mosquito-borne
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …