[HTML][HTML] Pathophysiological mechanisms of chronic compressive spinal cord injury due to vascular events

ZX Ren, JH Xu, X Cheng, GX Xu… - Neural Regeneration …, 2023 - journals.lww.com
Cervical spondylotic myelopathy is the main cause of non-traumatic spinal cord injury, with
chronic static and/or dynamic compressive spinal cord injury as the unique pathogenesis. In …

[HTML][HTML] Spinal cord parenchyma vascular redistribution underlies hemodynamic and neurophysiological changes at dynamic neck positions in cervical spondylotic …

Z Yu, X Cheng, J Chen, Z Huang, S He, H Hu… - Frontiers in …, 2021 - frontiersin.org
Cervical spondylotic myelopathy (CSM) is a degenerative condition of the spine that caused
by static and dynamic compression of the spinal cord. However, the mechanisms of motor …

Notch4 participates in mesenchymal stem cell-induced differentiation in 3D-printed matrix and is implicated in eccrine sweat gland morphogenesis

Y Wang, F Zhang, B Yao, L Hou, Z Li, W Song… - Burns & …, 2023 - academic.oup.com
Background Eccrine sweat gland (SG) plays a crucial role in thermoregulation but exhibits
very limited regenerative potential. Although SG lineage-restricted niches dominate SG …

[HTML][HTML] The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury

Z Yu, X Cheng, W Pan, C Yu… - Neural Regeneration …, 2023 - journals.lww.com
Chronic compressive spinal cord injury in compressive cervical myelopathy conditions can
lead to rapid neurological deterioration in the early phase, followed by partial self-recovery …

Zonisamide improves Fas/FasL-mediated apoptosis and inflammation in a degenerative cervical myelopathy rat model

Z Wang, Y Tan, F Xu - Tissue and Cell, 2023 - Elsevier
Degenerative cervical myelopathy (DCM) is a severe condition of the spinal cord caused by
chronic compression. However, no studies to date have examined the effects of zonisamide …

[HTML][HTML] Blood spinal cord barrier disruption recovers in patients with degenerative cervical myelopathy after surgical decompression: a prospective cohort study

TP Schmidt, K Jütten, U Bertram, LO Brandenburg… - Scientific Reports, 2023 - nature.com
The pathophysiology of degenerative cervical myelopathy (DCM) is characterized by chronic
compression-induced damage to the spinal cord leading to secondary harm such as …

抑制铁死亡有利于慢性压迫性脊髓损伤后神经功能的恢复

Z Yu, X Cheng, W Pan, C Yu, Y Duan - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
脊髓型颈椎病是成人最常见的导致脊髓功能障碍的疾病之一, 其病理机制在于脊髓受到椎管内骨
性结构或软组织的慢性压迫. 铁死亡是许多神经退行性疾病的一个重要病理过程; 然而 …

慢性压迫性脊髓损伤的血管事件及其病理生理学机制

ZX Ren, JH Xu, X Cheng, GX Xu… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
颈椎病是非外伤性脊髓损伤的主要原因. 慢性静态和/或动态压迫性脊髓损伤是颈椎病的独特
发病机制; 在这种情况的发展过程中, 微血管网络被压缩和破坏, 导致同时出现缺血和缺氧 …

[HTML][HTML] Drug discovery in spinal cord injury with ankylosing spondylitis identified by text mining and biomedical databases

C Wang, H Ma, W Wu, X Lu - Frontiers in Genetics, 2022 - frontiersin.org
Spinal cord injury (SCI) and ankylosing spondylitis (AS) are common inflammatory diseases
in spine surgery. However, it is a project where the relationship between the two diseases is …

Inhibition of Notch pathway alleviates nab-paclitaxel-induced peripheral neuropathic pain in rats via suppressing HMGB1/TLR4 signaling in spinal cord

X Wei, Y Zhou, L Ma, W Li, C Shan, S Zhang, Y Zhao - 2022 - researchsquare.com
Paclitaxel is widely used in clinical treatment of cancer and peripheral neuropathy is a
common adverse side effect of paclitaxel. Diverse mechanisms contribute to the …