Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

In recent years, gene therapy has made remarkable achievements in tumor treatment. In a
successfully cancer gene therapy, a smart gene delivery system is necessary for both …

Notwithstanding immune checkpoint blocking (ICB) therapy has made eminent clinical
breakthroughs, overcoming immunologically “cold” tumors remains challenging. Here, a …

Tracking and imaging immune cells in vivo non-invasively would offer insights into the
immune responses induced by vaccination. Here we report a cancer vaccine consisting of …

Development of a nanoscale drug delivery system that can simultaneously exert efficient
tumor therapeutic efficacy while creating the desired antitumor immune responses is still …

Nanovaccines, a new generation of vaccines that use nanoparticles as carriers and/or
adjuvants, have been widely used in the prevention and treatment of various diseases …

Dendritic cells (DCs) are crucial mediators of innate and adaptive antitumor immunity,
whereas exogenously and endogenously driven lipid accumulation causes immune …

DNA origami is a cutting-edge DNA self-assembly technique that neatly folds DNA strands
and creates specific structures based on the complementary base pairing principle. These …

T lymphocyte recruitment and infiltration promises to suppress the most devastating
metastatic tumors for immunotherapy. However, the immune privilege and low vaccine …

Immunotherapy has been considered as a potent antitumor modality while its efficacy is
frequently hampered by the insufficient immunogenicity and immunosuppressive tumor …