Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective
Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …
drugs are available on the market but they either lack specificity or have poor safety, severe …
Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …
heterocyclic compound with a wide range of pharmacological prospective such as …
Recent advances in the synthesis of biologically and pharmaceutically active quinoline and its analogues: a review
A Weyesa, E Mulugeta - RSC advances, 2020 - pubs.rsc.org
Recently, quinoline has become an essential heterocyclic compound due to its versatile
applications in the fields of industrial and synthetic organic chemistry. It is a vital scaffold for …
applications in the fields of industrial and synthetic organic chemistry. It is a vital scaffold for …
The biological activity of natural alkaloids against herbivores, cancerous cells and pathogens
A Thawabteh, S Juma, M Bader, D Karaman, L Scrano… - Toxins, 2019 - mdpi.com
The growing incidence of microorganisms that resist antimicrobials is a constant concern for
the scientific community, while the development of new antimicrobials from new chemical …
the scientific community, while the development of new antimicrobials from new chemical …
Green recipes to quinoline: A review
The quinoline core possesses a vast number of biological activities such as anticancer,
antimalarial, antimicrobial, antifungal, antitubercular and antileishmanial. The conventional …
antimalarial, antimicrobial, antifungal, antitubercular and antileishmanial. The conventional …
Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies
SI Eissa, AM Farrag, SY Abbas, MF El Shehry… - Bioorganic …, 2021 - Elsevier
One of the best ways to design new biocidal agents is synthesizing hybrid molecules by
combining two or more bioactive moieties in a single molecular scaffold. So, new series of …
combining two or more bioactive moieties in a single molecular scaffold. So, new series of …
Seeking heterocyclic scaffolds as antivirals against dengue virus
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Computational investigation of bioactive 2, 3-diaryl quinolines using DFT method: FT-IR, NMR spectra, NBO, NLO, HOMO-LUMO transitions, and quantum-chemical …
S Janeoo, A Saroa, R Kumar, H Kaur - Journal of Molecular Structure, 2022 - Elsevier
Quinoline derivatives are widely utilized in a variety of applications, including medicine and
materials. In this work our previously developed bioactive fluorine-containing 2, 3 …
materials. In this work our previously developed bioactive fluorine-containing 2, 3 …
Synthetic and medicinal perspective of quinolines as antiviral agents
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …
Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …