Mutations of the KCNE1 gene (IsK, minK) are related to hereditary forms of cardiac
arrhythmias, so-called long QT syndromes (LQT). Here we review the phenotype of a mouse …

Over the past 10 years, cDNAs encoding a wide range of pore-forming K+-channel α-
subunits have been cloned and found to result in currents with many properties of …

Several ion transporters have been implicated in left-right (LR) patterning. Here, we
characterize a new component of the early bioelectrical circuit: the potassium channel …

Epithelial cells in the kidney, gastrointestinal tract and exocrine glands are engaged in
vectorial transport of salt and nutrients. In these tissues, K+ channels play an important role …

In the heart, several K+ channels are responsible for the repolarization of the cardiac action
potential, including transient outward and delayed rectifier K+ currents. In the present study …

Previous studies demonstrated that mice with a null mutation in the gene encoding the
hormone gastrin have impaired gastric acid secretion. Hence, the aim of this study was to …

The colonic mucosa protects itself from the luminal content by secreting mucus that keeps
the bacteria at a distance from the epithelium. For this barrier to be effective, the mucus has …

Non‐Technical Summary High levels of oestrogen are known to cause fluid retention in
fertile females. It is thought that the increase in body fluid volume is necessary for proper …

Abstract Background/Aims: Heteromeric KCNEx/KCNQ1 (= KvLQT1, Kv7. 1) K+ channels
are important for repolarization of cardiac myocytes, endolymph secretion in the inner ear …

In the cochlea, sensory transduction depends on the endocochlear potential (EP) and the
unique composition of the endolymph, both of which are maintained by a highly specialized …