Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

The management of patients with brain metastases has become a major issue due to the
increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014 …

The incidence of brain metastases has markedly increased in the past 20 years owing to
progress in the treatment of malignant solid tumours, earlier diagnosis by MRI and an …

Brain metastases (BMs) occur in 10% to 20% of adult patients with cancer, and with
increased surveillance and improved systemic control, the incidence is likely to grow …

Introduction Leptomeningeal metastases (LM) have increased in patients with NSCLC, and
prognostic factors and outcomes for LM with EGFR gene mutations have not been well …

An estimated 20% of patients with cancer will develop brain metastases. Approximately
200,000 individuals in the United States alone receive whole-brain radiotherapy (WBRT) …

The clinical management/understanding of brain metastases (BM) has changed
substantially in the last 5 years, with key advances and clinical trials highlighted in this …

作者单位: 100021 北京, 中国医学科学院北京协和医学院肿瘤医院, 抗肿瘤分子靶向药物临床
研究北京市重点实验室(石远凯, 孙燕, 韩晓红, 郏博, 韩颖, 黄昱); 250117 济南 …

This systematic review aims to improve understanding of the burden of disease associated
with brain metastases from non-small-cell lung cancer (NSCLC) in terms of survival, quality …