We have investigated the effect of the G/A substitution in the promoter region of the
apolipoprotein (apo) AI gene (− 75 bp) on plasma lipid, lipoprotein and apolipoprotein levels …

The liver is where a large number of metabolic regulatory processes take place. Here, a set
of enzymes are constitutively expressed or induced whose function is to metabolize the …

We have analyzed determinants of the synthesis and secretion of apolipoproteins including
mRNA for apolipoproteins, in the human colon carcinoma cell line Caco-2 during …

Liver-specific expression of the apolipoprotein AI (apoAI) gene is mediated by transcription
factors bound to three sites (A, B, and C) in the apoAI enhancer. Sites A and C bind various …

Apolipoprotein (apo) A1 plays a central role in the metabolism of HDL. We describe a novel
genetic variant of the apoA1 gene identified in a patient with low concentrations of plasma …

The human coagulation protease factor VII plays a pivotal role in the initiation of the
coagulation cascade by both the extrinsic and the intrinsic pathway. Although the gene …

The regulation of macrophage lipoprotein lipase by cytokines is of potentially crucial
importance in the pathogenesis of atherosclerosis. We have shown previously that …

The influence of the guanidine to adenine (G/A) substitution in the promoter region of the
apolipoprotein (apo) AI gene (at− 75 bp) on serum lipids and apolipoproteins was studied in …

Previous studies have shown that the A to G transition occurring at position− 75 bp upstream
of the transcriptional start site in the human apolipoprotein AI gene may affect plasma high …

HDL regulation is exerted at multiple levels including regulation at the level of transcription
initiation by transcription factors and signal transduction cascades; regulation at the …