Delivery of oligonucleotide therapeutics: chemical modifications, lipid nanoparticles, and extracellular vesicles
Oligonucleotides (ONs) comprise a rapidly growing class of therapeutics. In recent years, the
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …
Cubosomes: the next generation of smart lipid nanoparticles?
HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …
Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …
promising class of advanced materials for the next generation of nanomedicine, comprising …
Real‐Time pH‐Dependent Self‐Assembly of Ionisable Lipids from COVID‐19 Vaccines and In Situ Nucleic Acid Complexation
Ionisable amino‐lipid is a key component in lipid nanoparticles (LNPs), which plays a crucial
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
Inverse cubic and hexagonal mesophase evolution within ionizable lipid nanoparticles correlates with mRNA transfection in macrophages
mRNA lipid nanoparticle (LNP) technology presents enormous opportunities to prevent and
treat various diseases. Here, we developed a novel series of LNPs containing ionizable …
treat various diseases. Here, we developed a novel series of LNPs containing ionizable …
Food liposomes: Structures, components, preparations, and applications
This review explores liposomes, focusing on their structure, components, the characteristics
influencing their stability and applicability in foods, and preparation methods. The role of …
influencing their stability and applicability in foods, and preparation methods. The role of …
pH-responsive drug delivery systems as intelligent carriers for targeted drug therapy: Brief history, properties, synthesis, mechanism and application
There are different pH-sensitive systems for biomedical applications that have recently been
considered for pH targeting nanomedicine. In this review, we examine some of the most …
considered for pH targeting nanomedicine. In this review, we examine some of the most …
General overview of lipid–polymer hybrid nanoparticles, dendrimers, micelles, liposomes, spongosomes and cubosomes
RR Wakaskar - Journal of drug targeting, 2018 - Taylor & Francis
Introduction: In recent years, the wider use of nanotechnology has attracted greater attention
from scientists in multi-disciplinary fields. Nanotechnological research has come a long way …
from scientists in multi-disciplinary fields. Nanotechnological research has come a long way …
Preparation, characterization, and antimicrobial activity of cubosome encapsulated metal nanocrystals
Herein, we demonstrate a method for the functionalization of cubic phase lipid nanoparticles
(cubosomes) with a series of magnetite (Fe3O4), copper oxide (Cu2O), and silver (Ag) …
(cubosomes) with a series of magnetite (Fe3O4), copper oxide (Cu2O), and silver (Ag) …
Advances in lyotropic liquid crystal systems for skin drug delivery
ABSTRACT Introduction Lyotropic liquid crystals (LLCs) are organized mesophases with
intermediate properties between liquids and solids. The LLC and its liquid crystalline …
intermediate properties between liquids and solids. The LLC and its liquid crystalline …