This paper represents an international collaboration of paediatric endocrine and other
societies (listed in the Appendix) under the International Consortium of Paediatric …

Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by the
deficient production, secretion or action of gonadotropin-releasing hormone (GnRH), which …

The hypothalamus is one of the most complex brain structures involved in homeostatic
regulation. Defining cell composition and identifying cell-type-specific transcriptional …

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of
women of reproductive age. It generally manifests with oligo/anovulatory cycles, hirsutism …

Hypothalamic kisspeptin neurons serve as the nodal regulatory centre of reproductive
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …

BACKGROUND Autophagy is an intracellular catabolic process of degrading and recycling
proteins and organelles to modulate various physiological and pathological events …

In this paper, we discuss the surging hormones of puberty and their influences on
adolescent behavior. We describe why these issues represent an interesting and important …

Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …

The hypothalamus (“hypo” meaning below, and “thalamus” meaning bed) consists of
regulatory circuits that support basic life functions that ensure survival. Sitting at the interface …

Primary cilia are specialized microtubule‐based signaling organelles that convey
extracellular signals into a cellular response in most vertebrate cell types. The physiological …