Biofilm microenvironment-responsive nanoparticles for the treatment of bacterial infection

Y Hu, X Ruan, X Lv, Y Xu, W Wang, Y Cai, M Ding… - Nano Today, 2022 - Elsevier
Highlights•The biofilm formation process and its microenvironmental characteristics are
described.•Biofilm microenvironment-responsive nanoparticles for anti-infection are …

[HTML][HTML] Biofilms: the microbial “protective clothing” in extreme environments

W Yin, Y Wang, L Liu, J He - International journal of molecular sciences, 2019 - mdpi.com
Microbial biofilms are communities of aggregated microbial cells embedded in a self-
produced matrix of extracellular polymeric substances (EPS). Biofilms are recalcitrant to …

Biofilms: Formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

Oxidative stress

H Sies, C Berndt, DP Jones - Annual review of biochemistry, 2017 - annualreviews.org
Oxidative stress is two sided: Whereas excessive oxidant challenge causes damage to
biomolecules, maintenance of a physiological level of oxidant challenge, termed oxidative …

Unexpected insights into antibacterial activity of zinc oxide nanoparticles against methicillin resistant Staphylococcus aureus (MRSA)

U Kadiyala, ES Turali-Emre, JH Bahng, NA Kotov… - Nanoscale, 2018 - pubs.rsc.org
Zinc oxide nanoparticles (ZnO-NPs) are attractive as broad-spectrum antibiotics, however,
their further engineering as antimicrobial agents and clinical translation is impeded by …

[HTML][HTML] Surviving reactive chlorine stress: responses of gram-negative bacteria to hypochlorous acid

WS da Cruz Nizer, V Inkovskiy, J Overhage - Microorganisms, 2020 - mdpi.com
Sodium hypochlorite (NaOCl) and its active ingredient, hypochlorous acid (HOCl), are the
most commonly used chlorine-based disinfectants. HOCl is a fast-acting and potent …

Oxidative stress generation of silver nanoparticles in three bacterial genera and its relationship with the antimicrobial activity

MA Quinteros, VC Aristizábal, PR Dalmasso… - Toxicology in vitro, 2016 - Elsevier
Oxidative stress is a condition caused by the high intracellular concentrations of reactive
oxygen species (ROS) that includes superoxide anion radicals, hydroxyl radicals and …

Anode potentials regulate Geobacter biofilms: new insights from the composition and spatial structure of extracellular polymeric substances

G Yang, L Huang, Z Yu, X Liu, S Chen, J Zeng, S Zhou… - Water research, 2019 - Elsevier
The extracellular electron transfer (EET) efficiency in bioelectrochemical systems has been
proven to be dependent on anode potentials. To explore the underlying mechanism …

How microbial aggregates protect against nanoparticle toxicity

J Tang, Y Wu, S Esquivel-Elizondo, SJ Sørensen… - Trends in …, 2018 - cell.com
The increasing use and discharge of nanoparticles (NPs) pose risks to microorganisms that
maintain the health of aquatic ecosystems. Although NPs are toxic to microorganisms, they …

Antibiofilm effects of quercetin against Salmonella enterica biofilm formation and virulence, stress response, and quorum-sensing gene expression

YK Kim, PK Roy, M Ashrafudoulla, S Nahar… - Food Control, 2022 - Elsevier
Salmonellosis is a prevalent food poisoning disease caused by Salmonella spp. that affects
millions of people throughout the world. Contamination of chicken meat and processing …