Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?

PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

[HTML][HTML] Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections

KD Goughenour, AS Nair, J Xu, MA Olszewski… - Journal of Fungi, 2023 - mdpi.com
Fungal infections are an increasingly growing public health concern, and Cryptococcus is
one of the most problematic fungal organisms causing substantial mortality and morbidity …

[HTML][HTML] Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic …

RJA de Castro, CL Marina, A Sturny-Leclère… - PLoS …, 2023 - journals.plos.org
Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease
caused by Cryptococcus neoformans. This opportunistic infection can arise following the …

[HTML][HTML] Host–Pathogen Interactions and Correlated Factors That Are Affected in Replicative-Aged Cryptococcus neoformans

VKA Silva, S Min, K Yoo, BC Fries - Journal of Fungi, 2024 - mdpi.com
Cryptococcus neoformans is a facultative intracellular fungal pathogen. Ten-generation-old
(10GEN) C. neoformans cells are more resistant to phagocytosis and killing by …