The importance of antimicrobial resistance in medical mycology

NAR Gow, C Johnson, J Berman, AT Coste… - Nature …, 2022 - nature.com
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance

P Koehler, M Bassetti, A Chakrabarti… - The Lancet Infectious …, 2021 - thelancet.com
Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway
epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary …

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

J Rhodes, A Abdolrasouli, K Dunne, TR Sewell… - Nature …, 2022 - nature.com
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

COVID-19 associated pulmonary aspergillosis (CAPA)—from immunology to treatment

A Arastehfar, A Carvalho, FL van de Veerdonk… - Journal of Fungi, 2020 - mdpi.com
Like severe influenza, coronavirus disease-19 (COVID-19) resulting in acute respiratory
distress syndrome (ARDS) has emerged as an important disease that predisposes patients …

Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

PE Verweij, BJA Rijnders, RJM Brüggemann… - Intensive care …, 2020 - Springer
Purpose Invasive pulmonary aspergillosis is increasingly reported in patients with influenza
admitted to the intensive care unit (ICU). Classification of patients with influenza-associated …

Sixty years of amphotericin B: an overview of the main antifungal agent used to treat invasive fungal infections

FB Cavassin, JL Baú-Carneiro, RR Vilas-Boas… - Infectious Diseases and …, 2021 - Springer
Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management

GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis

PE Verweij, RJM Brüggemann, E Azoulay… - Intensive care …, 2021 - Springer
Purpose Invasive pulmonary aspergillosis (IPA) is increasingly reported in patients with
severe coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU) …

Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …