Polymeric systems for bioprinting

ML Bedell, AM Navara, Y Du, S Zhang… - Chemical …, 2020 - ACS Publications
Bioprinting is rapidly being adopted as a major method for fabricating tissue engineering
constructs. Through the precise deposition of cell-and bioactive molecule-laden materials …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016 - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

High and low molecular weight hyaluronic acid differentially influence macrophage activation

JE Rayahin, JS Buhrman, Y Zhang… - ACS biomaterials …, 2015 - ACS Publications
Macrophages exhibit phenotypic diversity permitting wide-ranging roles in maintaining
physiologic homeostasis. Hyaluronic acid, a major glycosaminoglycan of the extracellular …

Natural polymers for the microencapsulation of cells

L Gasperini, JF Mano, RL Reis - Journal of the royal …, 2014 - royalsocietypublishing.org
The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an
attractive procedure for many biomedical and biotechnological applications, such as …

Designing smart polymer conjugates for controlled release of payloads

F Seidi, R Jenjob, D Crespy - Chemical reviews, 2018 - ACS Publications
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

Hyaluronan: a simple polysaccharide with diverse biological functions

KT Dicker, LA Gurski, S Pradhan-Bhatt, RL Witt… - Acta biomaterialia, 2014 - Elsevier
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid
and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the …

Designing degradable hydrogels for orthogonal control of cell microenvironments

PM Kharkar, KL Kiick, AM Kloxin - Chemical Society Reviews, 2013 - pubs.rsc.org
Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …

Hyaluronan, a crucial regulator of inflammation

AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …

Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment

A Fakhari, C Berkland - Acta biomaterialia, 2013 - Elsevier
Hyaluronic acid (HA) is a naturally occurring biodegradable polymer with a variety of
applications in medicine, including scaffolding for tissue engineering, dermatological fillers …

Enzymatically crosslinked silk-hyaluronic acid hydrogels

NR Raia, BP Partlow, M McGill, EP Kimmerling… - Biomaterials, 2017 - Elsevier
In this study, silk fibroin and hyaluronic acid (HA) were enzymatically crosslinked to form
biocompatible composite hydrogels with tunable mechanical properties similar to that of …