[HTML][HTML] Mechanisms and disease consequences of nonalcoholic fatty liver disease

R Loomba, SL Friedman, GI Shulman - Cell, 2021 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …

[HTML][HTML] Nuclear receptors linking metabolism, inflammation, and fibrosis in nonalcoholic fatty liver disease

T Puengel, H Liu, A Guillot, F Heymann… - International journal of …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) and its progressive form nonalcoholic
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …

Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring

T Huang, W Zhang, T Lin, S Liu, Z Sun, F Liu… - Food and Chemical …, 2022 - Elsevier
Nanoplastics have raised considerable concerns since their ubiquity in the environment and
potential hazard to health. It has been proven that polystyrene nanoparticles (PS-NPs) can …

[HTML][HTML] UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma

J Xu, L Ji, Y Ruan, Z Wan, Z Lin, S Xia, L Tao… - Signal transduction and …, 2021 - nature.com
The treatment for hepatocellular carcinoma (HCC) is promising in recent years, but still
facing critical challenges. The first targeted therapy, sorafenib, prolonged the overall survival …

Recovery of Bacteroides thetaiotaomicron ameliorates hepatic steatosis in experimental alcohol-related liver disease

M Sangineto, C Grander, F Grabherr, L Mayr… - Gut …, 2022 - Taylor & Francis
Alcohol-related liver disease (ALD) is a major cause of liver disease and represents a global
burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop …

[HTML][HTML] Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies

J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending?

M Longo, M Meroni, E Paolini, C Macchi… - Metabolism, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) includes a broad spectrum of liver dysfunctions
and it is predicted to become the primary cause of liver failure and hepatocellular carcinoma …

[HTML][HTML] Mediterranean diet and mitochondria: new findings

F Pollicino, N Veronese, LJ Dominguez… - Experimental …, 2023 - Elsevier
Mitochondria are subcellular organelles known for their central role in several energetic
processes. Accumulating evidence supports a key role for mitochondria in the physiological …

[HTML][HTML] Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy

Y Zheng, S Wang, J Wu, Y Wang - Journal of Translational Medicine, 2023 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …

[HTML][HTML] The potential of the Mediterranean diet to improve mitochondrial function in experimental models of obesity and metabolic syndrome

M Khalil, H Shanmugam, H Abdallah, JS John Britto… - Nutrients, 2022 - mdpi.com
The abnormal expansion of body fat paves the way for several metabolic abnormalities
including overweight, obesity, and diabetes, which ultimately cluster under the umbrella of …