[HTML][HTML] Mechanisms and disease consequences of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
[HTML][HTML] Nuclear receptors linking metabolism, inflammation, and fibrosis in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) and its progressive form nonalcoholic
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …
steatohepatitis (NASH) comprise a spectrum of chronic liver diseases in the global …
Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring
T Huang, W Zhang, T Lin, S Liu, Z Sun, F Liu… - Food and Chemical …, 2022 - Elsevier
Nanoplastics have raised considerable concerns since their ubiquity in the environment and
potential hazard to health. It has been proven that polystyrene nanoparticles (PS-NPs) can …
potential hazard to health. It has been proven that polystyrene nanoparticles (PS-NPs) can …
[HTML][HTML] UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma
J Xu, L Ji, Y Ruan, Z Wan, Z Lin, S Xia, L Tao… - Signal transduction and …, 2021 - nature.com
The treatment for hepatocellular carcinoma (HCC) is promising in recent years, but still
facing critical challenges. The first targeted therapy, sorafenib, prolonged the overall survival …
facing critical challenges. The first targeted therapy, sorafenib, prolonged the overall survival …
Recovery of Bacteroides thetaiotaomicron ameliorates hepatic steatosis in experimental alcohol-related liver disease
M Sangineto, C Grander, F Grabherr, L Mayr… - Gut …, 2022 - Taylor & Francis
Alcohol-related liver disease (ALD) is a major cause of liver disease and represents a global
burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop …
burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop …
[HTML][HTML] Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies
J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …
caused as consequences of chronic liver diseases. Although HCC is more common in …
Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending?
Nonalcoholic fatty liver disease (NAFLD) includes a broad spectrum of liver dysfunctions
and it is predicted to become the primary cause of liver failure and hepatocellular carcinoma …
and it is predicted to become the primary cause of liver failure and hepatocellular carcinoma …
[HTML][HTML] Mediterranean diet and mitochondria: new findings
F Pollicino, N Veronese, LJ Dominguez… - Experimental …, 2023 - Elsevier
Mitochondria are subcellular organelles known for their central role in several energetic
processes. Accumulating evidence supports a key role for mitochondria in the physiological …
processes. Accumulating evidence supports a key role for mitochondria in the physiological …
[HTML][HTML] Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy
Y Zheng, S Wang, J Wu, Y Wang - Journal of Translational Medicine, 2023 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …
metabolic disease globally, and its associated complications including insulin resistance …
[HTML][HTML] The potential of the Mediterranean diet to improve mitochondrial function in experimental models of obesity and metabolic syndrome
M Khalil, H Shanmugam, H Abdallah, JS John Britto… - Nutrients, 2022 - mdpi.com
The abnormal expansion of body fat paves the way for several metabolic abnormalities
including overweight, obesity, and diabetes, which ultimately cluster under the umbrella of …
including overweight, obesity, and diabetes, which ultimately cluster under the umbrella of …