Strategies to reduce blood loss and transfusion of allogeneic blood products during surgical
procedures are important in modern times. The most important and well-known autologous …

TGF-β1 is a ubiquitous growth factor that is implicated in the control of proliferation,
migration, differentiation, and survival of many different cell types. It influences such diverse …

Abstract Treatment of large bone defects, particularly bone non-union, remains a clinical
challenge. The gold-standard bone substitute continues to be an autologous bone graft …

In addition to their well-known function in hemostasis, platelets also release substances that
promote tissue repair, angiogenesis, and inflammation (1). At the site of the injury, platelets …

The first step in bone healing is forming a blood clot at injured bones. During bone
implantation, biomaterials unavoidably come into direct contact with blood, leading to a …

Background: Alveolar bone loss can be a major clinical concern affecting both functionality
and esthetics. Osteoblasts are the main cells charged with the repair and regeneration of …

Background: Platelet-leukocyte gel (PLG) is being used during various surgical procedures
in an attempt to enhance the healing process. We studied the effects of PLG on …

Bone healing is a complex repair process that commences with the formation of a blood clot
at the injured bone, termed hematoma. It has evidenced that a lack of a stable hematoma …

The objective of the described experiments was to determine the electrical parameters that
lead to optimal expression of a number of bone‐related genes in cultured human bone cells …

Platelet-rich plasma (PRP) is clinically used as an autologous blood product to stimulate
bone formation in vivo. In the present study, we examined the effects of PRP on proliferation …