Background Clostridioides difficile is considered an urgent threat to human health by the US
Centers for Disease Control and Prevention. In recent years, C. difficile has been reported …

Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021,
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …

Background Dozens of studies have demonstrated gut dysbiosis in COVID-19 patients
during the acute and recovery phases. However, a consensus on the specific COVID-19 …

There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing
significant economic impact on the health care system. Although toxigenic C. diff carriage is …

The rising prevalence of antibiotic resistant microbial pathogens presents an ominous health
and economic challenge to modern society. The discovery and large-scale development of …

It has recently become evident that the bacterial stringent response is regulated by a
triphosphate alarmone (pGpp) as well as the canonical tetra-and pentaphosphate …

Examining the interplay between intestinal pathogens and the gut microbiota is crucial to
fully comprehend the pathogenic role of enteropathogens and their broader impact on …

Background Fecal microbiota transplantation (FMT) and fecal virome transplantation (FVT,
sterile filtrated donor feces) have been effective in treating recurrent Clostridioides difficile …

Crystal structures of camelid heavy-chain antibody variable domains (VHHs) bound to
fragments of the combined repetitive oligopeptides domain of Clostridioides difficile toxin A …

Clostridioides difficile (Clostridium difficile) infection (CDI) is one of the main public health
concerns in adults, while children under 2 years of age are often colonized …