Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Myeloid cell-targeted therapies for solid tumours

S Goswami, S Anandhan, D Raychaudhuri… - Nature Reviews …, 2023 - nature.com
Myeloid cells are the most abundant immune components of the tumour microenvironment,
where they have a variety of functions, ranging from immunosuppressive to …

Tumor‐associated macrophages in liver cancer: from mechanisms to therapy

K Cheng, N Cai, J Zhu, X Yang, H Liang… - Cancer …, 2022 - Wiley Online Library
Multidimensional analyses have demonstrated the presence of a unique tumor
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …

Monocyte programming by cancer therapy

M Patysheva, A Frolova, I Larionova… - Frontiers in …, 2022 - frontiersin.org
Monocytes in peripheral blood circulation are the precursor of essential cells that control
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …

The role of osteopontin in tumor progression through tumor-associated macrophages

Y Tan, L Zhao, YG Yang, W Liu - Frontiers in Oncology, 2022 - frontiersin.org
Osteopontin (OPN) is a multifunctional phosphorylated protein. It is widely involved in solid
tumor progression, such as intensification of macrophage recruitment, inhibition of T-cell …

Targeting macrophages: a novel treatment strategy in solid tumors

M Liu, L Liu, Y Song, W Li, L Xu - Journal of Translational Medicine, 2022 - Springer
In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …

Tumor microenvironment in ovarian cancer peritoneal metastasis

S Mei, X Chen, K Wang, Y Chen - Cancer cell international, 2023 - Springer
Ovarian cancer (OC) is one of the most common gynecological malignancies with high
morbidity and mortality. The peritoneum is one of the most common metastatic sites in …

[HTML][HTML] Targeting the tumor microenvironment: Potential strategy for cancer therapeutics

Q Babar, A Saeed, TA Tabish, M Sarwar… - Biochimica et Biophysica …, 2023 - Elsevier
Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …

Tumor-associated macrophages (TAMs) in cancer resistance; modulation by natural products

HA Lafta, AH AbdulHussein… - Current topics in …, 2023 - ingentaconnect.com
Tumor-associated macrophages (TAMs) play a pivotal role in the progression and
resistance of tumors to different anticancer drugs. TAMs can modulate the tumor …

Targeting inflammation as cancer therapy

M Wang, S Chen, X He, Y Yuan, X Wei - Journal of Hematology & …, 2024 - Springer
Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …