Stealth and pseudo-stealth nanocarriers
The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …
applications through improving the pharmacokinetics such as blood circulation …
Emerging ultrasmall luminescent nanoprobes for in vivo bioimaging
Photoluminescence (PL) imaging has become a fundamental tool in disease diagnosis,
therapeutic evaluation, and surgical navigation applications. However, it remains a big …
therapeutic evaluation, and surgical navigation applications. However, it remains a big …
Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona
Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein
corona. The protein corona has been shown to determine the biological identity and in vivo …
corona. The protein corona has been shown to determine the biological identity and in vivo …
Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent
Extracellular vesicles (EVs) derived from mesenchymal stem cells are promising
nanotherapeutics in liver diseases due to their regenerative and immunomodulatory …
nanotherapeutics in liver diseases due to their regenerative and immunomodulatory …
The interplay between PEGylated nanoparticles and blood immune system
C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery
Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …
Approved nanomedicine against diseases
Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …
Nanotechnology represents one of the most effective approaches in elevating a drug's …
Cancer nanomedicine: emerging strategies and therapeutic potentials
M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective
treatments more critical than ever. Traditional therapies, although pivotal in managing …
treatments more critical than ever. Traditional therapies, although pivotal in managing …
A targeted exosome therapeutic confers both CfDNA scavenging and macrophage polarization for ameliorating rheumatoid arthritis
Z Wang, C Zhang, J Meng, Z Jiao, W Bao… - Advanced …, 2023 - Wiley Online Library
Only a minority of rheumatoid arthritis (RA) patients achieve disease remission, so the
exploration of additional pathogenic factors and the development of new therapeutics are …
exploration of additional pathogenic factors and the development of new therapeutics are …
Multifunctional nanoparticle-mediated combining therapy for human diseases
X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …
disease prevention and treatment. In preclinical investigations, combined effect of certain …