MicroRNAs as modulators of longevity and the aging process
HE Kinser, Z Pincus - Human genetics, 2020 - Springer
MicroRNAs (miRNAs) are short, non-coding RNAs that post-transcriptionally repress
translation or induce mRNA degradation of target transcripts through sequence-specific …
translation or induce mRNA degradation of target transcripts through sequence-specific …
[HTML][HTML] Circular RNAs: a novel player in development and disease of the central nervous system
Circular RNAs (circRNAs) own unique capabilities to communicate with nucleic acids and
ribonucleoproteins and are emerging as indispensable compositions of the regulatory …
ribonucleoproteins and are emerging as indispensable compositions of the regulatory …
[HTML][HTML] MicroRNAs in age-related proteostasis and stress responses
Aging is associated with the accumulation of damaged and misfolded proteins through a
decline in the protein homeostasis (proteostasis) machinery, leading to various age …
decline in the protein homeostasis (proteostasis) machinery, leading to various age …
[HTML][HTML] tRNA-derived fragments as New Hallmarks of Aging and Age-related Diseases
Y Yuan, J Li, Z He, X Fan, X Mao, M Yang… - Aging and …, 2021 - ncbi.nlm.nih.gov
Abstract tRNA-derived fragments (tRFs), which are non-coding RNAs produced via tRNA
cleavage with lengths of 14 to 50 nucleotides, originate from precursor tRNAs or mature …
cleavage with lengths of 14 to 50 nucleotides, originate from precursor tRNAs or mature …
[HTML][HTML] Dynamics of tRNA fragments and their targets in aging mammalian brain
S Karaiskos, A Grigoriev - F1000Research, 2016 - ncbi.nlm.nih.gov
Background: The progress of next-generation sequencing technologies has unveiled
various non-coding RNAs that have previously been considered products of random …
various non-coding RNAs that have previously been considered products of random …
[HTML][HTML] MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication
Abstract Enterovirus 71 (EV71) is the predominant causative pathogen of hand-foot-and-
mouth disease (HFMD). Contrary to other HFMD-causing enterovirus, EV71 can lead to …
mouth disease (HFMD). Contrary to other HFMD-causing enterovirus, EV71 can lead to …
[HTML][HTML] Molecular signatures of the aging brain: finding the links between genes and phenotypes
Aging is associated with cognitive decline and increased vulnerability to neurodegenerative
diseases. The progressive extension of the average human lifespan is bound to lead to a …
diseases. The progressive extension of the average human lifespan is bound to lead to a …
MicroRNA Expression Profiling Screen miR‐3557/324‐Targeted CaMK/mTOR in the Rat Striatum of Parkinson's Disease in Regular Aerobic Exercise
W Liu, L Li, S Liu, Z Wang, H Kuang… - BioMed research …, 2019 - Wiley Online Library
This study aimed to screen the target miRNAs and to investigate the differential miR‐
3557/324‐targeted signal mechanisms in the rats' model of Parkinson's disease (PD) with …
3557/324‐targeted signal mechanisms in the rats' model of Parkinson's disease (PD) with …
[HTML][HTML] The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis
D Yang, F Xiao, Y Yuan, J Li, S Wang, X Fan… - International Journal of …, 2023 - mdpi.com
tRNA-derived small RNAs (tsRNAs) are derived from tRNA and include tRNA halves
(tiRNAs) and tRNA fragments (tRFs). tsRNAs have been implicated in a variety of important …
(tiRNAs) and tRNA fragments (tRFs). tsRNAs have been implicated in a variety of important …
[HTML][HTML] Endoplasmic reticulum stress and miRNA impairment in aging and age-related diseases
Aging is a physiological process defined by decreased cellular and tissue functions.
Reduced capacity of protein degradation is one of the important hallmarks of aging that may …
Reduced capacity of protein degradation is one of the important hallmarks of aging that may …