Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults

KP Lopes, L Yu, X Shen, Y Qiu, S Tasaki… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION The secreted phosphoprotein 1 (SPP1) gene expressed by CD11c+ cells
is known to be associated with microglia activation and neuroinflammatory diseases. As …

[HTML][HTML] Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits

RA Vialle, K de Paiva Lopes, Y Li, B Ng, JA Schneider… - medRxiv, 2024 - ncbi.nlm.nih.gov
Advances have led to a greater understanding of the genetics of Alzheimer's Disease (AD).
However, the gap between the predicted and observed genetic heritability estimates when …