Ketamine: a review of clinical pharmacokinetics and pharmacodynamics in anesthesia and pain therapy

MA Peltoniemi, NM Hagelberg, KT Olkkola… - Clinical …, 2016 - Springer
Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-
methyl-d-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the …

Perioperative intravenous ketamine for acute postoperative pain in adults

ECV Brinck, E Tiippana, M Heesen… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

Consensus guidelines on the use of intravenous ketamine infusions for acute pain management from the American Society of Regional Anesthesia and Pain Medicine …

ES Schwenk, ER Viscusi, A Buvanendran… - Regional Anesthesia & …, 2018 - rapm.bmj.com
Background Ketamine infusions have been used for decades to treat acute pain, but a
recent surge in usage has made the infusions a mainstay of treatment in emergency …

Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings)

G Mion, T Villevieille - CNS neuroscience & therapeutics, 2013 - Wiley Online Library
For more than 50 years, ketamine has proven to be a safe anesthetic drug with potent
analgesic properties. The active enantiomer is S (+)‐ketamine. Ketamine is mostly …

[PDF][PDF] A systematic review of intravenous ketamine for postoperative analgesia

K Laskowski, A Stirling, WP Mckay… - Canadian Journal of …, 2011 - academia.edu
Résumé Objectif La ketamine intraveineuse perioperatoire peut constituer un ajout utile
al'arsenal therapeutique de prise en charge de la douleur. Les revues methodiques …

Anaesthesia, surgery, and challenges in postoperative recovery

H Kehlet, JB Dahl - The Lancet, 2003 - thelancet.com
Surgical injury can be followed by pain, nausea, vomiting and ileus, stress-induced
catabolism, impaired pulmonary function, increased cardiac demands, and risk of …

Multimodal analgesia for controlling acute postoperative pain

A Buvanendran, JS Kroin - Current opinion in Anesthesiology, 2009 - journals.lww.com
Multimodal analgesia for controlling acute postoperative pai... : Current Opinion in
Anesthesiology Multimodal analgesia for controlling acute postoperative pain : Current Opinion …

The use of intravenous infusion or single dose of low-dose ketamine for postoperative analgesia: a review of the current literature

J Jouguelet-Lacoste, L La Colla, D Schilling… - Pain …, 2015 - academic.oup.com
Objective As an analgesic and N-methyl-D-aspartate receptor antagonist, ketamine has
been increasingly used as an adjunct in the management of acute perioperative pain …

Preemptive analgesia

I Kissin, RB Weiskopf - The Journal of the American Society of …, 2000 - pubs.asahq.org
Preemptive Analgesia | Anesthesiology | American Society of Anesthesiologists Skip to Main
Content Advertisement Umbrella Alt Text Umbrella Alt Text Close Anesthesiology ASA Monitor …

Consequences of inadequate postoperative pain relief and chronic persistent postoperative pain

GP Joshi, BO Ogunnaike - … Clinics of North …, 2005 - anesthesiology.theclinics.com
Postoperative pain is still inadequately relieved despite substantial improvements in the
knowledge of the mechanisms and treatment of pain [1]. Evidence suggests that inadequate …