Enzyme engineering: Reshaping the biocatalytic functions

M Ali, HM Ishqi, Q Husain - Biotechnology and bioengineering, 2020 - Wiley Online Library
Enzyme engineering is a powerful tool to fine‐tune the enzymes. It is a technique by which
the stability, activity, and specificity of the enzymes can be altered. The characteristic …

Enantioselective enzymatic desymmetrizations in organic synthesis

E García-Urdiales, I Alfonso, V Gotor - Chemical Reviews, 2005 - ACS Publications
During the recent past years, tremendous efforts have been made to establish
enantioselective routes for the preparation of enantiomerically pure compounds due to their …

[图书][B] Organic electrochemistry

O Hammerich, B Speiser - 2016 - api.taylorfrancis.com
Organic electrochemistry is concerned with the reduction and oxidation of organic molecules
at electrodes. Although it is now more than 200 years ago that the so-called Volta pile was …

Industrial biotechnology—the future of green chemistry?

S Wenda, S Illner, A Mell, U Kragl - Green Chemistry, 2011 - pubs.rsc.org
Biocatalysis fulfils many key criteria of green chemistry, but this raises the question: how
efficient are such production methods and how important is biotechnology for greener …

Whole-cell biocatalysis for selective and productive C–O functional group introduction and modification

M Schrewe, MK Julsing, B Bühler… - Chemical Society Reviews, 2013 - pubs.rsc.org
During the last decades, biocatalysis became of increasing importance for chemical and
pharmaceutical industries. Regarding regio-and stereospecificity, enzymes have shown to …

Biocatalytic ketone reduction—a powerful tool for the production of chiral alcohols—part I: processes with isolated enzymes

K Goldberg, K Schroer, S Lütz, A Liese - Applied microbiology and …, 2007 - Springer
Enzymes are able to perform reactions under mild conditions, eg, pH and temperature, with
remarkable chemo-, regio-, and stereoselectivity. Because of this feature, the number of …

Biocatalytic strategies for the asymmetric synthesis of α-hydroxy ketones

P Hoyos, JV Sinisterra, F Molinari… - Accounts of chemical …, 2010 - ACS Publications
The development of efficient syntheses for enantiomerically enriched α-hydroxy ketones is
an important research focus in the pharmaceutical industry. For example, α-hydroxy ketones …

Enantioenriched compounds via enzyme-catalyzed redox reactions

M Hall, AS Bommarius - Chemical reviews, 2011 - ACS Publications
Redox reactions are essential to any currently known form of life and are at the core of a
majority of metabolic processes, such as cellular respiration or photosynthesis. As about …

Asymmetric synthesis of chiral cyclic amine from cyclic imine by bacterial whole-cell catalyst of enantioselective imine reductase

K Mitsukura, M Suzuki, K Tada, T Yoshida… - Organic & …, 2010 - pubs.rsc.org
Streptomyces sp. GF3587 and 3546 were found to be imine-reducing strains with high R-
and S-selectivity by screening using 2-methyl-1-pyrroline (2-MPN). Their whole-cell catalysts …

Process technology for multi-enzymatic reaction systems

R Xue, JM Woodley - Bioresource Technology, 2012 - Elsevier
In recent years, biocatalysis has started to provide an important green tool in synthetic
organic chemistry. Currently, the idea of using multi-enzymatic systems for industrial …