In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art

S Snykers, J De Kock, V Rogiers, T Vanhaecke - Stem cells, 2009 - academic.oup.com
Stem cells are a unique source of self-renewing cells within the human body. Before the end
of the last millennium, adult stem cells, in contrast to their embryonic counterparts, were …

[HTML][HTML] Extracellular matrix stiffness in lung health and disease

T Guo, C He, A Venado, Y Zhou - Comprehensive Physiology, 2022 - ncbi.nlm.nih.gov
The extracellular matrix (ECM) provides structural support and imparts a wide variety of
environmental cues to cells. In the past decade, a growing body of work revealed that the …

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

M Kim, JY Lee, CN Jones, A Revzin, G Tae - Biomaterials, 2010 - Elsevier
Primary hepatocytes are commonly used as liver surrogates in toxicology and tissue
engineering fields, therefore, maintenance of functional hepatocytes in vitro is an important …

Transition metal complexes of a multidentate Schiff base ligand containing guanidine moiety: Synthesis, characterization, anti-cancer effect, and anti-microbial activity

SE Abd El-Razek, SM El-Gamasy, M Hassan… - Journal of Molecular …, 2020 - Elsevier
Guanidine Schiff bases are famous for their distinctive features and medicinal benefits with
potential applications for the control of bacterial infections and cancer development. The …

Neurite outgrowth on a DNA crosslinked hydrogel with tunable stiffnesses

FX Jiang, B Yurke, BL Firestein… - Annals of biomedical …, 2008 - Springer
Mechanical cues arising from extracellular matrices greatly affect cellular properties, and
hence, are of significance in designing biomaterials. In this study, a DNA crosslinked …

[HTML][HTML] Effect of substrate stiffness on early human embryonic stem cell differentiation

N Eroshenko, R Ramachandran, VK Yadavalli… - Journal of biological …, 2013 - Springer
Background The pluripotency and self renewing properties of human embryonic stem cells
(hESC) make them a valuable tool in the fields of developmental biology, pharmacology and …

High‐precision 3D bio‐dot printing to improve paracrine interaction between multiple types of cell spheroids

S Jeon, JH Heo, MK Kim, W Jeong… - Advanced functional …, 2020 - Wiley Online Library
Cell–cell interaction accounts for one of the most influential factors affecting the viability and
functionality of cell‐based tissue models. In this respect, various methods capable of …

Encapsulated mesenchymal stromal cells for in vivo transplantation

J Barminko, JH Kim, S Otsuka, A Gray… - Biotechnology and …, 2011 - Wiley Online Library
Immunomodulatory human mesenchymal stromal cells (hMSC) have been incorporated into
therapeutic protocols to treat secondary inflammatory responses post‐spinal cord injury …

Modulation of human iPSC-derived hepatocyte phenotype via extracellular matrix microarrays

CP Monckton, A Brougham-Cook, GH Underhill… - Acta biomaterialia, 2022 - Elsevier
In vitro human liver models are essential for drug screening, disease modeling, and cell-
based therapies. Induced pluripotent stem cell (iPSC)-derived hepatocyte-like cells (iHeps) …

HPLC-DAD-ESI-MS/MS characterization of bioactive secondary metabolites from Strelitzia nicolai leaf extracts and their antioxidant and anticancer activities in vitro

M Ghareeb, A Saad, W Ahmed, L Refahy… - Pharmacognosy …, 2018 - phcogres.com
Background: Strelitzia nicolai Regel and Körn (Strelitziaceae) is native to Southern Africa
whose phytochemistry and pharmacology were slightly investigated. Materials and Methods …