When it was initially discovered in 1923, inhibin was characterized as a hypophysiotropic
hormone that acts on pituitary cells to regulate pituitary hormone secretion. Ninety years …

Ovarian age is classically considered the main cause of female reproductive infertility. In
women, the process proceeds as an ongoing decline in the primordial follicle stockpile and it …

STUDY QUESTION Does resveratrol counteract age-associated infertility in a mouse model
of reproductive aging? SUMMARY ANSWER Long-term-oral administration of resveratrol …

Purpose Germline mutations in BRCA genes are associated with breast and ovarian cancer
susceptibility. Because infertility is associated with breast and ovarian cancer risks, we …

Background With infertility populations in the developed world rapidly aging, treatment of
diminished ovarian reserve (DOR) assumes increasing clinical importance …

BACKGROUND Ovarian aging is associated with declining numbers and quality of oocytes
and follicles. Oxidative stress by reactive oxygen species (ROS) contributes to somatic aging …

Though a widely utilized term and clinical concept, ovarian reserve (OR) has been only
inadequately defined. Based on Medline and PubMed searches we here define OR in its …

BACKGROUND The aim of the present study was to determine the intrafollicular
concentrations of anti-Müllerian hormone (AMH), inhibin-B and steroids in normal human …

The concept of ovarian reserve describes the natural oocyte endowment and is closely
associated with female age, which is the single most important factor influencing …

Maximal receiver operating characteristic curve inflections, which differentiate between
better and poorer delivery chances in women with diminished ovarian reserve (DOR) …