Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications
The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance
Social hierarchy is established as an outcome of individual social behaviors, such as
dominance behavior during long-term interactions with others. Astrocytes are implicated in …
dominance behavior during long-term interactions with others. Astrocytes are implicated in …
Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder
Major depressive disorder emerges from the complex interactions of biological systems that
span genes and molecules through cells, networks, and behavior. Establishing how …
span genes and molecules through cells, networks, and behavior. Establishing how …
Beyond the three-chamber test: toward a multimodal and objective assessment of social behavior in rodents
R Jabarin, S Netser, S Wagner - Molecular Autism, 2022 - Springer
Main In recent years, substantial advances in social neuroscience have been realized,
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …
Reciprocal cortico-amygdala connections regulate prosocial and selfish choices in mice
D Scheggia, F La Greca, F Maltese… - Nature …, 2022 - nature.com
Decisions that favor one's own interest versus the interest of another individual depend on
context and the relationships between individuals. The neurobiology underlying selfish …
context and the relationships between individuals. The neurobiology underlying selfish …
Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition
Prefrontal cortex (PFC) is postulated to exert" top-down control" on information processing
throughout the brain to promote specific behaviors. However, pathways mediating top-down …
throughout the brain to promote specific behaviors. However, pathways mediating top-down …
Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
The medial prefrontal cortex as a central hub for mental comorbidities associated with chronic pain
KK Kummer, M Mitrić, T Kalpachidou… - International journal of …, 2020 - mdpi.com
Chronic pain patients frequently develop and suffer from mental comorbidities such as
depressive mood, impaired cognition, and other significant constraints of daily life, which …
depressive mood, impaired cognition, and other significant constraints of daily life, which …
[HTML][HTML] Neural mechanisms necessary for empathy-related phenomena across species
The neural basis of empathy and prosociality has received much interest over the past
decades. Neuroimaging studies localized a network of brain regions with activity that …
decades. Neuroimaging studies localized a network of brain regions with activity that …